CES1, carboxylesterase 1, 1066

N. diseases: 80; N. variants: 6
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0028754
Disease: Obesity
Obesity 		disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases Disease or Syndrome 2821 1111 0.340 None 1.000 4 2010 2018
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		disease Nutritional and Metabolic Diseases Disease or Syndrome 489 123 0.310 None 1.000 2 2003 2018
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 199 39 0.300 None 1.000 2 2003 2003
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		group Neoplasms; Respiratory Tract Diseases Neoplastic Process 1486 39 0.300 None 1.000 2 2007 2007
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		group Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 121 0.300 None 1.000 2 2003 2003
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		disease Neoplasms; Respiratory Tract Diseases Neoplastic Process 4173 1142 0.300 None 1.000 2 2007 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 144 3 0.300 None 1.000 2 2003 2003
CUI: C0025521
Disease: Inborn Errors of Metabolism
Inborn Errors of Metabolism 		group Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases Disease or Syndrome; Congenital Abnormality 119 3 0.300 None 1.000 1 2008 2008
CUI: C0027412
Disease: Opioid-Related Disorders
Opioid-Related Disorders 		group Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 12 23 0.300 None 1.000 1 2003 2003
CUI: C0029095
Disease: Opioid abuse
Opioid abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 16 0.300 None 1.000 1 2003 2003
CUI: C0524661
Disease: Narcotic Abuse
Narcotic Abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 6 0.300 None 1.000 1 2003 2003
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 81 46 0.300 None 1.000 1 2003 2003
CUI: C1527402
Disease: Narcotic Dependence
Narcotic Dependence 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 7 1 0.300 None 1.000 1 2003 2003
CUI: C4551628
Disease: Opiate Abuse
Opiate Abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 12 0.300 None 1.000 1 2003 2003
CUI: C0025303
Disease: Meningococcal Infections
Meningococcal Infections 		group Infections Disease or Syndrome 69 32 0.100 None 1.000 1 1 2010 2010
CUI: C4748035
Disease: DRUG METABOLISM, ALTERED, CES1-RELATED
DRUG METABOLISM, ALTERED, CES1-RELATED 		phenotype Finding 1 2 0.100 None 0 2
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases Neoplastic Process 1293 222 0.060 None 1.000 6 1991 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		group Neoplasms Neoplastic Process 10161 1644 0.050 None 1.000 5 2005 2019
CUI: C0043208
Disease: Wolman Disease
Wolman Disease 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases Disease or Syndrome 19 35 0.040 None 1.000 4 1972 1995
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		disease Cardiovascular Diseases Disease or Syndrome 2006 267 0.040 None 1.000 4 2009 2017
CUI: C0023452
Disease: Childhood Acute Lymphoblastic Leukemia
Childhood Acute Lymphoblastic Leukemia 		disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases Neoplastic Process 1096 261 0.040 None 1.000 4 1991 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		disease Cardiovascular Diseases Disease or Syndrome 2044 281 0.040 None 1.000 4 2009 2017
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		disease Neoplastic Process 860 154 0.040 None 1.000 4 1991 2018
CUI: C1292769
Disease: Precursor B-cell lymphoblastic leukemia
Precursor B-cell lymphoblastic leukemia 		disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases Neoplastic Process 478 23 0.030 None 1.000 3 1998 2018
CUI: C1263846
Disease: Attention deficit hyperactivity disorder
Attention deficit hyperactivity disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 842 420 0.030 None 1.000 3 2 2009 2013