COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C3160814
Disease: Cannabis use
Cannabis use 		disease Mental or Behavioral Dysfunction 74 44 0.400 None 1.000 13 1 2005 2019
CUI: C0871189
Disease: Psychotic symptom
Psychotic symptom 		phenotype Sign or Symptom 86 21 0.100 None 0.917 12 1 1991 2019
CUI: C0042693
Disease: Violence
Violence 		phenotype Mental or Behavioral Dysfunction 70 6 0.060 None 0.667 6 1 1997 2012
CUI: C0233401
Disease: Psychiatric symptom
Psychiatric symptom 		phenotype Sign or Symptom 95 12 0.050 None 1.000 5 1 2005 2019
CUI: C0424101
Disease: Inattention
Inattention 		phenotype Mental or Behavioral Dysfunction 66 22 0.040 None 1.000 4 1 1999 2014
CUI: C3160718
Disease: PARKINSON DISEASE, LATE-ONSET
PARKINSON DISEASE, LATE-ONSET 		disease Disease or Syndrome 247 76 0.040 None 0.750 4 1 2001 2012
CUI: C0564567
Disease: Impulsive character (finding)
Impulsive character (finding) 		phenotype Mental or Behavioral Dysfunction 52 19 0.030 None 1.000 3 1 2010 2013
CUI: C0741682
Disease: Premenopausal breast cancer
Premenopausal breast cancer 		disease Neoplastic Process 51 18 0.030 None 0.667 3 1 2001 2009
CUI: C0746402
Disease: manic symptom
manic symptom 		phenotype Mental or Behavioral Dysfunction 16 1 0.030 None 1.000 3 1 2006 2017
CUI: C0815107
Disease: psychological distress
psychological distress 		disease Mental or Behavioral Dysfunction 87 10 0.030 None 1.000 3 1 2014 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		phenotype Neoplastic Process 6626 169 0.030 None 1.000 3 2010 2015
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		disease Disease or Syndrome 1075 276 0.030 None 1.000 3 3 2011 2014
CUI: C2748208
Disease: Executive dysfunction
Executive dysfunction 		disease Mental or Behavioral Dysfunction 33 3 0.030 None 1.000 3 1 2007 2019
CUI: C4284120
Disease: Ecstasy related disorders
Ecstasy related disorders 		disease Mental or Behavioral Dysfunction 15 0.030 None 0.667 3 2009 2012
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		disease Neoplastic Process 3669 502 0.030 None 1.000 3 2014 2019
CUI: C0234133
Disease: Extrapyramidal sign
Extrapyramidal sign 		phenotype Sign or Symptom 116 7 0.020 None 1.000 2 1 2008 2009
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use 		disease Mental or Behavioral Dysfunction 108 21 0.020 None 0.500 2 2014 2019
CUI: C3544321
Disease: Treatment-resistant schizophrenia
Treatment-resistant schizophrenia 		disease Mental or Behavioral Dysfunction 23 2 0.020 None 1.000 2 1 2003 2018
CUI: C4694057
Disease: Taq1A POLYMORPHISM
Taq1A POLYMORPHISM 		disease Disease or Syndrome 9 14 0.020 None 1.000 2 1 2011 2013
CUI: C0005893
Disease: Body mass index procedure
Body mass index procedure 		phenotype Diagnostic Procedure 88 252 0.100 None 1.000 1 1 2014 2014
CUI: C0023222
Disease: Pain in lower limb
Pain in lower limb 		phenotype Sign or Symptom 31 2 0.010 None < 0.001 1 2014 2014
CUI: C0027401
Disease: Narcissism
Narcissism 		phenotype Mental or Behavioral Dysfunction 10 0.010 None 1.000 1 2008 2008
CUI: C0085923
Disease: soft neurological signs
soft neurological signs 		phenotype Sign or Symptom 15 1 0.010 None 1.000 1 2007 2007
CUI: C0149779
Disease: Somatization
Somatization 		disease Mental or Behavioral Dysfunction 21 5 0.010 None 1.000 1 2011 2011
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		group Mental or Behavioral Dysfunction 360 56 0.010 None 1.000 1 2018 2018