ACE, angiotensin I converting enzyme, 1636

N. diseases: 1082; N. variants: 82
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		phenotype Disease or Syndrome 716 25 0.100 None 0.962 26 1994 2020
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		disease Neoplastic Process 3669 502 0.100 None 0.818 11 1 2007 2020
CUI: C1096293
Disease: Macroangiopathy
Macroangiopathy 		disease Disease or Syndrome 31 6 0.070 None 1.000 7 1 1995 2003
CUI: C4728082
Disease: Severe hypoglycaemia
Severe hypoglycaemia 		disease Disease or Syndrome 36 2 0.070 None 1.000 7 1 2001 2011
CUI: C0741949
Disease: Cardiovascular Pathology
Cardiovascular Pathology 		disease Disease or Syndrome 23 0.060 None 1.000 6 1996 2005
CUI: C4509226
Disease: Heart failure with preserved ejection fraction [HFpEF]
Heart failure with preserved ejection fraction [HFpEF] 		disease Disease or Syndrome 89 4 0.060 None 0.833 6 1 2016 2018
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis 		disease Disease or Syndrome 297 3 0.050 None 1.000 5 2013 2019
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		disease Disease or Syndrome 1075 276 0.050 None 1.000 5 2001 2010
CUI: C0852283
Disease: Respiratory Distress Syndrome
Respiratory Distress Syndrome 		disease Disease or Syndrome 58 9 0.040 None 1.000 4 2006 2015
CUI: C3178782
Disease: Aortic Stiffness
Aortic Stiffness 		phenotype Disease or Syndrome 61 11 0.040 None 1.000 4 1996 2011
CUI: C4699152
Disease: ST-segment elevation myocardial infarction (STEMI)
ST-segment elevation myocardial infarction (STEMI) 		disease Disease or Syndrome 51 2 0.040 None 1.000 4 2009 2019
CUI: C0877008
Disease: Enzyme inhibition disorder
Enzyme inhibition disorder 		phenotype Disease or Syndrome 171 1 0.030 None 1.000 3 2017 2020
CUI: C0878552
Disease: Coronary artery ectasia
Coronary artery ectasia 		disease Disease or Syndrome 24 1 0.030 None 1.000 3 2005 2017
CUI: C1301700
Disease: Cardiovascular morbidity
Cardiovascular morbidity 		phenotype Disease or Syndrome 75 2 0.030 None 1.000 3 2005 2018
CUI: C1504533
Disease: Post transplant erythrocytosis
Post transplant erythrocytosis 		disease Disease or Syndrome 3 0.030 None 1.000 3 2003 2018
CUI: C2609253
Disease: Macrovascular disease
Macrovascular disease 		disease Disease or Syndrome 23 1 0.030 None 1.000 3 1998 2007
CUI: C3160845
Disease: PAI-1 4G/5G polymorphism
PAI-1 4G/5G polymorphism 		disease Disease or Syndrome 6 3 0.030 None 1.000 3 1998 2019
CUI: C4700045
Disease: Non-ST-segment elevation myocardial infarction (NSTEMI)
Non-ST-segment elevation myocardial infarction (NSTEMI) 		disease Disease or Syndrome 18 1 0.030 None 0.667 3 2018 2020
CUI: C0008060
Disease: child abuse behavior
child abuse behavior 		phenotype Mental or Behavioral Dysfunction 40 11 0.020 None 1.000 2 2018 2018
CUI: C0220810
Disease: Congenital defects
Congenital defects 		group Congenital Abnormality 126 6 0.020 None 1.000 2 2017 2017
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use 		disease Mental or Behavioral Dysfunction 108 21 0.020 None 1.000 2 2018 2018
CUI: C0282666
Disease: Very Low Birth Weight
Very Low Birth Weight 		phenotype Sign or Symptom 42 2 0.020 None 0.500 2 2001 2005
CUI: C0282667
Disease: Infant, Very Low Birth Weight
Infant, Very Low Birth Weight 		disease Disease or Syndrome 26 1 0.020 None 0.500 2 2004 2005
CUI: C0338657
Disease: Age-associated memory impairment
Age-associated memory impairment 		disease Disease or Syndrome 9 0.020 None 1.000 2 1999 2000
CUI: C0374997
Disease: Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 		disease Disease or Syndrome 593 24 0.020 None 1.000 2 2011 2017