ALK, ALK receptor tyrosine kinase, 238

N. diseases: 519; N. variants: 41
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		phenotype Neoplastic Process 6626 169 0.100 None 1.000 19 2006 2019
CUI: C2749484
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO
NEUROBLASTOMA, SUSCEPTIBILITY TO 		phenotype Finding 11 34 0.100 None 1.000 11 14 1990 2016
CUI: C0677932
Disease: Progressive Neoplastic Disease
Progressive Neoplastic Disease 		phenotype Neoplastic Process 384 40 0.080 None 1.000 8 2 2014 2018
CUI: C2751681
Disease: NEUROBLASTOMA, SUSCEPTIBILITY TO, 3
NEUROBLASTOMA, SUSCEPTIBILITY TO, 3 		disease Finding 1 16 0.600 definitive 1.000 8 16 2008 2012
CUI: C3539781
Disease: Progressive cGVHD
Progressive cGVHD 		disease Disease or Syndrome 384 40 0.080 None 1.000 8 2 2014 2018
CUI: C4518436
Disease: Anaplastic lymphoma kinase positive anaplastic large cell lymphoma
Anaplastic lymphoma kinase positive anaplastic large cell lymphoma 		disease Neoplastic Process 8 0.070 None 1.000 7 2009 2018
CUI: C1332216
Disease: Adult Systemic Anaplastic Large Cell Lymphoma
Adult Systemic Anaplastic Large Cell Lymphoma 		disease Neoplastic Process 12 0.060 None 1.000 6 2007 2019
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		phenotype Neoplastic Process 1027 20 0.060 None 1.000 6 1994 2016
CUI: C1512127
Disease: HER2 gene amplification
HER2 gene amplification 		disease Disease or Syndrome 170 14 0.050 None 1.000 5 2012 2019
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		disease Neoplastic Process 3669 502 0.050 None 1.000 5 2012 2015
CUI: C0281710
Disease: Childhood Large Cell Lymphoma
Childhood Large Cell Lymphoma 		disease Neoplastic Process 30 0.040 None 0.750 4 1996 2001
CUI: C0854988
Disease: Adenocarcinoma of lung, stage IV
Adenocarcinoma of lung, stage IV 		disease Neoplastic Process 19 6 0.040 None 1.000 4 2015 2020
CUI: C0028259
Disease: Nodule
Nodule 		phenotype Acquired Abnormality 278 19 0.030 None 1.000 3 2016 2019
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor 		phenotype Neoplastic Process 735 33 0.030 None 0.667 3 2014 2019
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH) 		disease Disease or Syndrome 1075 276 0.030 None 1.000 3 2009 2011
CUI: C4522245
Disease: Atypical Spitz Nevus
Atypical Spitz Nevus 		disease Neoplastic Process 9 0.030 None 0.667 3 2015 2019
CUI: C0002690
Disease: Amputation Stumps
Amputation Stumps 		disease Acquired Abnormality 11 0.020 None 0.500 2 2015 2019
CUI: C0677730
Disease: Aggressive Adult Non-Hodgkin Lymphoma
Aggressive Adult Non-Hodgkin Lymphoma 		disease Neoplastic Process 16 0.020 None 1.000 2 2005 2011
CUI: C0742468
Disease: Central nervous system lesion
Central nervous system lesion 		disease Disease or Syndrome 34 1 0.020 None 1.000 2 2018 2018
CUI: C1332225
Disease: Aggressive Non-Hodgkin Lymphoma
Aggressive Non-Hodgkin Lymphoma 		disease Neoplastic Process 57 1 0.020 None 1.000 2 2005 2011
CUI: C1336052
Disease: Spindle Cell Neoplasm
Spindle Cell Neoplasm 		disease Neoplastic Process 19 0.020 None 0.500 2 2012 2018
CUI: C1514517
Disease: Prostate Stromal Proliferation of Uncertain Malignant Potential
Prostate Stromal Proliferation of Uncertain Malignant Potential 		disease Neoplastic Process 3 0.020 None 0.500 2 2015 2019
CUI: C2826323
Disease: Refractory Cytopenia of Childhood
Refractory Cytopenia of Childhood 		disease Neoplastic Process 264 3 0.020 None 1.000 2 2015 2019
CUI: C4688308
Disease: Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Advanced Lung Non-Squamous Non-Small Cell Carcinoma 		disease Neoplastic Process 10 1 0.020 None 1.000 2 2013 2018
CUI: C0220645
Disease: Childhood Soft Tissue Sarcoma
Childhood Soft Tissue Sarcoma 		disease Neoplastic Process 166 3 0.010 None 1.000 1 2019 2019