GRN, granulin precursor, 2896

N. diseases: 412; N. variants: 66
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C3539123
Disease: CEROID LIPOFUSCINOSIS, NEURONAL, 11
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		disease Disease or Syndrome 1 8 0.700 None 1.000 13 8 2006 2017
CUI: C4303804
Disease: Deficiency of cathepsin D
Deficiency of cathepsin D 		disease Disease or Syndrome 1 0.010 None 1.000 1 2017 2017
CUI: C0562457
Disease: Manic behavior
Manic behavior 		disease Mental or Behavioral Dysfunction 2 0.010 None 1.000 1 2018 2018
CUI: C1843793
Disease: Progressive language deterioration
Progressive language deterioration 		phenotype Finding 2 0.100 None 0
CUI: C4022574
Disease: Limb apraxia
Limb apraxia 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Disease or Syndrome 3 1 0.020 None 1.000 2 2008 2013
CUI: C0001825
Disease: Agraphia
Agraphia 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Mental or Behavioral Dysfunction 3 1 0.010 None 1.000 1 2011 2011
CUI: C1850792
Disease: Congenital myasthenic syndrome ib
Congenital myasthenic syndrome ib 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases Disease or Syndrome 3 30 0.300 limited 0
CUI: C0268279
Disease: Lipofuscinosis
Lipofuscinosis 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases Disease or Syndrome 4 0.060 None 1.000 6 2010 2019
CUI: C4274665
Disease: Logopenic progressive aphasia
Logopenic progressive aphasia 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Mental or Behavioral Dysfunction 4 0.010 None 1.000 1 2011 2011
CUI: C3824872
Disease: Obesity in animals
Obesity in animals 		disease Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases Disease or Syndrome 5 0.010 None 1.000 1 2018 2018
CUI: C4518562
Disease: Pneumonia caused by Gram positive bacteria
Pneumonia caused by Gram positive bacteria 		disease Infections; Respiratory Tract Diseases Disease or Syndrome 5 0.010 None 1.000 1 2017 2017
CUI: C0002625
Disease: Amnestic Disorder
Amnestic Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 6 0.010 None 1.000 1 2008 2008
CUI: C1969697
Disease: Repetitive compulsive behavior
Repetitive compulsive behavior 		disease Mental Disorders Mental or Behavioral Dysfunction 6 4 0.100 None 0
CUI: C0851980
Disease: Peritoneal Infection
Peritoneal Infection 		group Infections Disease or Syndrome 7 0.010 None 1.000 1 2020 2020
CUI: C1843792
Disease: FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		disease Disease or Syndrome 8 23 0.980 moderate 1.000 24 23 2006 2018
CUI: C0338630
Disease: Senile Paranoid Dementia
Senile Paranoid Dementia 		disease Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 8 0.300 None 1.000 2 2007 2008
CUI: C0003113
Disease: Anomia
Anomia 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Mental or Behavioral Dysfunction 8 0.110 None 1.000 1 2007 2007
CUI: C4324721
Disease: Radiologically isolated syndrome
Radiologically isolated syndrome 		disease Immune System Diseases; Nervous System Diseases Disease or Syndrome 8 0.010 None 1.000 1 2018 2018
CUI: C0234502
Disease: Visual Agnosia
Visual Agnosia 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Sign or Symptom 8 0.100 None 0
CUI: C0312420
Disease: Hypersexuality state
Hypersexuality state 		disease Mental Disorders; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 8 2 0.100 None 0
CUI: C4072928
Disease: Spoken Word Recognition Deficit
Spoken Word Recognition Deficit 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Mental or Behavioral Dysfunction 8 0.100 None 0
CUI: C0002018
Disease: Alexia
Alexia 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 9 0.100 None 0
CUI: C0919974
Disease: Abulia
Abulia 		disease Mental or Behavioral Dysfunction 9 0.100 None 0
CUI: C0338457
Disease: Aphasia, Progressive
Aphasia, Progressive 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Mental or Behavioral Dysfunction 10 2 0.010 None 1.000 1 2012 2012
CUI: C1838320
Disease: Hyperorality
Hyperorality 		phenotype Behavior and Behavior Mechanisms Finding 10 0.100 None 0