APP, amyloid beta precursor protein, 351

N. diseases: 371; N. variants: 63
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease Mental Disorders; Nervous System Diseases Disease or Syndrome 1981 1062 0.900 0.967 1764 39 1987 2018
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD)
disease Mental Disorders; Nervous System Diseases Disease or Syndrome 187 62 0.600 0.972 210 16 1988 2018
CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED
disease Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1 5 0.600 15 5 1990 2010
Cerebral hemorrhage with amyloidosis, hereditary, Dutch type
disease Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1 3 0.600 6 3 1990 2010
CUI: C0233794
Disease: Memory impairment
Memory impairment
phenotype Behavior and Behavior Mechanisms; Nervous System Diseases; Pathological Conditions, Signs and Symptoms Mental or Behavioral Dysfunction 266 22 0.500 0.938 78 2 1993 2018
CUI: C0497327
Disease: Dementia
Dementia
disease Mental Disorders; Nervous System Diseases Mental or Behavioral Dysfunction 435 107 0.500 0.970 75 8 1993 2018
CUI: C0085220
Disease: Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy
disease Cardiovascular Diseases; Nervous System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 44 11 0.500 0.939 38 3 1993 2016
CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ITALIAN VARIANT
disease Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1 3 0.500 6 3 1990 2010
CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ARCTIC VARIANT
disease Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1 3 0.500 6 3 1990 2010
CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, FLEMISH VARIANT
disease Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1 3 0.500 6 3 1990 2010
CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, IOWA VARIANT
disease Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases Disease or Syndrome 1 3 0.500 6 3 1990 2010
CUI: C0751295
Disease: Memory Loss
Memory Loss
phenotype Behavior and Behavior Mechanisms; Nervous System Diseases; Pathological Conditions, Signs and Symptoms Sign or Symptom 125 2 0.490 1.000 24 2002 2018
CUI: C1863052
Disease: ALZHEIMER DISEASE, FAMILIAL, 1
ALZHEIMER DISEASE, FAMILIAL, 1
disease Mental Disorders; Nervous System Diseases Disease or Syndrome 4 14 0.410 1.000 48 12 1991 2008
CUI: C0002726
Disease: Amyloidosis
Amyloidosis
disease Nutritional and Metabolic Diseases Disease or Syndrome 832 120 0.400 0.971 914 22 1988 2018
CUI: C0333463
Disease: Senile Plaques
Senile Plaques
phenotype Pathological Conditions, Signs and Symptoms Acquired Abnormality 300 27 0.400 0.952 229 7 1988 2017
CUI: C2936349
Disease: Plaque, Amyloid
Plaque, Amyloid
phenotype Pathological Conditions, Signs and Symptoms Acquired Abnormality 234 23 0.400 0.930 187 9 1988 2016
CUI: C0011265
Disease: Presenile dementia
Presenile dementia
disease Mental Disorders; Nervous System Diseases Mental or Behavioral Dysfunction 361 102 0.400 0.982 89 8 1991 2018
CUI: C0750901
Disease: Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset
disease Mental Disorders; Nervous System Diseases Disease or Syndrome 115 55 0.400 0.960 83 11 1991 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
disease Mental Disorders Mental or Behavioral Dysfunction 670 121 0.400 0.939 83 8 1993 2018
CUI: C0494463
Disease: Alzheimer Disease, Late Onset
Alzheimer Disease, Late Onset
disease Mental Disorders; Nervous System Diseases Mental or Behavioral Dysfunction 252 110 0.400 1.000 54 1 1991 2018
CUI: C0009241
Disease: Cognition Disorders
Cognition Disorders
group Mental Disorders Mental or Behavioral Dysfunction 236 29 0.400 1.000 41 5 1995 2018
CUI: C0524851
Disease: Neurodegenerative Disorders
Neurodegenerative Disorders
group Nervous System Diseases Disease or Syndrome 744 41 0.400 0.913 25 1994 2016
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
group Mental Disorders Mental or Behavioral Dysfunction 395 79 0.400 0.909 11 2 2004 2016
CUI: C0002622
Disease: Amnesia
Amnesia
disease Behavior and Behavior Mechanisms; Mental Disorders; Nervous System Diseases; Pathological Conditions, Signs and Symptoms Mental or Behavioral Dysfunction 57 2 0.390 1.000 10 2002 2017
CUI: C1270972
Disease: Mild cognitive disorder
Mild cognitive disorder
disease Mental Disorders Mental or Behavioral Dysfunction 149 40 0.370 1.000 8 2004 2016