LEPR, leptin receptor, 3953

N. diseases: 416; N. variants: 57
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0751437
Disease: Adenohypophyseal Diseases
Adenohypophyseal Diseases 		group Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 1 0.300 None 1.000 1 1998 1998
CUI: C0751438
Disease: Posterior pituitary disease
Posterior pituitary disease 		group Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 1 0.300 None 1.000 1 1998 1998
CUI: C3838754
Disease: Congenital leptin deficiency
Congenital leptin deficiency 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities Disease or Syndrome; Congenital Abnormality 3 0.010 None 1.000 1 2018 2018
CUI: C4021095
Disease: Abnormal hypothalamus morphology
Abnormal hypothalamus morphology 		disease Anatomical Abnormality 4 1 0.100 None 0
CUI: C1567257
Disease: Granulosa Cell Cancer
Granulosa Cell Cancer 		disease Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases Neoplastic Process 5 0.300 None 1.000 1 2017 2017
CUI: C1997092
Disease: Hypertensive left ventricular hypertrophy
Hypertensive left ventricular hypertrophy 		disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Disease or Syndrome 5 1 0.010 None 1.000 1 1 2013 2013
CUI: C4074771
Disease: Sterility, Reproductive
Sterility, Reproductive 		phenotype Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Pathologic Function 5 0.300 None 1.000 1 2004 2004
CUI: C3274639
Disease: Neonatal Opiate Withdrawal Syndrome
Neonatal Opiate Withdrawal Syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities Mental or Behavioral Dysfunction 6 0.010 None 1.000 1 2019 2019
CUI: C1846550
Disease: Decreased T cell activation
Decreased T cell activation 		phenotype Finding 6 0.100 None 0
CUI: C4316791
Disease: Entamoeba histolytica Infection
Entamoeba histolytica Infection 		disease Infections Disease or Syndrome 8 0.020 None 1.000 2 2011 2014
CUI: C1449647
Disease: Secondary Peritonitis
Secondary Peritonitis 		disease Digestive System Diseases; Infections Disease or Syndrome 8 0.010 None 1.000 1 2011 2011
CUI: C1837802
Disease: Decreased serum leptin
Decreased serum leptin 		phenotype Finding 8 0.100 None 0
CUI: C3554225
Disease: LEPTIN RECEPTOR DEFICIENCY
LEPTIN RECEPTOR DEFICIENCY 		disease Disease or Syndrome 9 3 0.720 strong 1.000 6 3 1998 2019
CUI: C1504375
Disease: Diabetic macroangiopathy
Diabetic macroangiopathy 		disease Disease or Syndrome 9 2 0.010 None 1.000 1 2012 2012
CUI: C4505163
Disease: Food Addiction
Food Addiction 		disease Mental Disorders; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 9 3 0.010 None 1.000 1 2013 2013
CUI: C0948368
Disease: Kaufman-McKusick syndrome
Kaufman-McKusick syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Cardiovascular Diseases Disease or Syndrome 10 6 0.010 None 1.000 1 2011 2011
CUI: C4054476
Disease: Monogenic Obesity
Monogenic Obesity 		phenotype Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases Sign or Symptom 11 1 0.030 None 1.000 3 2003 2018
CUI: C1844666
Disease: Immune dysregulation
Immune dysregulation 		phenotype Finding 11 1 0.100 None 0
CUI: C0032962
Disease: Pregnancy Complications
Pregnancy Complications 		group Female Urogenital Diseases and Pregnancy Complications Pathologic Function 13 0.010 None 1.000 1 2007 2007
CUI: C0405581
Disease: Testicular dysfunction
Testicular dysfunction 		disease Male Urogenital Diseases; Endocrine System Diseases Disease or Syndrome 13 0.010 None 1.000 1 2018 2018
CUI: C0271673
Disease: Symmetric Diabetic Proximal Motor Neuropathy
Symmetric Diabetic Proximal Motor Neuropathy 		disease Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 14 0.300 None 1.000 1 2014 2014
CUI: C0271674
Disease: Asymmetric Diabetic Proximal Motor Neuropathy
Asymmetric Diabetic Proximal Motor Neuropathy 		disease Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 14 0.300 None 1.000 1 2014 2014
CUI: C0271678
Disease: Diabetic Mononeuropathy
Diabetic Mononeuropathy 		disease Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 14 0.300 None 1.000 1 2014 2014
CUI: C0271685
Disease: Diabetic Amyotrophy
Diabetic Amyotrophy 		disease Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 14 0.300 None 1.000 1 2014 2014
CUI: C0271686
Disease: Diabetic Autonomic Neuropathy
Diabetic Autonomic Neuropathy 		disease Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 14 0.300 None 1.000 1 2014 2014