LHB, luteinizing hormone subunit beta, 3972

N. diseases: 62; N. variants: 11
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0520933
Disease: Abnormal spermatogenesis
Abnormal spermatogenesis 		phenotype Male Urogenital Diseases Finding 5 0.100 None 0
CUI: C4021768
Disease: Abnormality of metabolism/homeostasis
Abnormality of metabolism/homeostasis 		phenotype Finding 171 5 0.100 None 0
CUI: C4023703
Disease: Abnormality of the Leydig cells
Abnormality of the Leydig cells 		disease Anatomical Abnormality 4 0.100 None 0
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 156 24 0.300 None 1.000 1 1996 1996
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 218 54 0.300 None 1.000 1 1996 1996
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 577 441 0.300 None 1.000 1 1996 1996
CUI: C1847540
Disease: Azoospermia, Nonobstructive
Azoospermia, Nonobstructive 		disease Male Urogenital Diseases Disease or Syndrome 91 22 0.010 None 1.000 1 2003 2003
CUI: C0428977
Disease: Bradycardia
Bradycardia 		phenotype Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Finding 63 2 0.300 None 1.000 1 1983 1983
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		disease Neoplasms; Skin and Connective Tissue Diseases Neoplastic Process 6776 2793 0.010 None 1.000 1 2001 2001
CUI: C0342543
Disease: Central Precocious Puberty
Central Precocious Puberty 		disease Endocrine System Diseases Disease or Syndrome 32 2 0.300 None 1.000 1 2008 2008
CUI: C0271527
Disease: Cryptogenic sexual precocity
Cryptogenic sexual precocity 		phenotype Endocrine System Diseases Disease or Syndrome 13 2 0.300 None 1.000 1 2008 2008
CUI: C4072890
Disease: Decreased circulating luteinizing hormone level
Decreased circulating luteinizing hormone level 		phenotype Finding 6 0.100 None 0
CUI: C4073137
Disease: Decreased serum testosterone level
Decreased serum testosterone level 		phenotype Finding 47 0.100 None 0
CUI: C0342527
Disease: Deficiency of testosterone biosynthesis
Deficiency of testosterone biosynthesis 		disease Endocrine System Diseases Disease or Syndrome 18 0.100 None 0
CUI: C0034012
Disease: Delayed Puberty
Delayed Puberty 		phenotype Endocrine System Diseases Pathologic Function 196 21 0.300 None 1.000 1 2004 2004
CUI: C0014175
Disease: Endometriosis
Endometriosis 		disease Female Urogenital Diseases and Pregnancy Complications Disease or Syndrome 1188 274 0.010 None 1.000 1 2002 2002
CUI: C0021361
Disease: Female infertility
Female infertility 		phenotype Female Urogenital Diseases and Pregnancy Complications Pathologic Function 37 2 0.300 None 1.000 1 1998 1998
CUI: C0917730
Disease: Female sterility
Female sterility 		phenotype Female Urogenital Diseases and Pregnancy Complications Finding 28 0.300 None 1.000 1 1998 1998
CUI: C0018418
Disease: Gynecomastia
Gynecomastia 		disease Skin and Connective Tissue Diseases Disease or Syndrome 121 8 0.100 None 0
CUI: C0020514
Disease: Hyperprolactinemia
Hyperprolactinemia 		disease Nervous System Diseases; Endocrine System Diseases Disease or Syndrome 48 10 0.300 None 1.000 1 1980 1980
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		group Cardiovascular Diseases Disease or Syndrome 2322 1085 0.300 None 1.000 1 1983 1983
CUI: C0020550
Disease: Hyperthyroidism
Hyperthyroidism 		disease Endocrine System Diseases Disease or Syndrome 279 27 0.010 None 1.000 1 2019 2019
CUI: C0020619
Disease: Hypogonadism
Hypogonadism 		disease Endocrine System Diseases Disease or Syndrome 305 24 0.350 None 1.000 8 1992 2018
CUI: C3489396
Disease: Hypogonadism, Isolated Hypogonadotropic
Hypogonadism, Isolated Hypogonadotropic 		disease Endocrine System Diseases Disease or Syndrome 42 8 0.300 None 1.000 4 1992 2008
CUI: C0271623
Disease: Hypogonadotropic hypogonadism
Hypogonadotropic hypogonadism 		disease Endocrine System Diseases Disease or Syndrome 178 18 0.420 None 0.667 6 2 1992 2008