OPRK1, opioid receptor kappa 1, 4986

N. diseases: 46; N. variants: 0
Source: CURATED ×
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0038587
Disease: Substance Withdrawal Syndrome
Substance Withdrawal Syndrome
disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 58 0.300 None 1.000 2 1998 2010
CUI: C0086189
Disease: Drug Withdrawal Symptoms
Drug Withdrawal Symptoms
phenotype Chemically-Induced Disorders; Mental Disorders Sign or Symptom 58 0.300 None 1.000 2 1998 2010
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures
disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Disease or Syndrome 101 0.300 None 1.000 2 1991 2007
CUI: C0234535
Disease: Clonic Seizures
Clonic Seizures
disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Disease or Syndrome 101 0.300 None 1.000 2 1991 2007
CUI: C0234533
Disease: Generalized seizures
Generalized seizures
disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Disease or Syndrome 101 6 0.300 None 1.000 2 1991 2007
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 0.300 None 1.000 1 1998 1998
CUI: C0234254
Disease: Radiating pain
Radiating pain
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 0.300 None 1.000 1 1998 1998
CUI: C0751407
Disease: Pain, Migratory
Pain, Migratory
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 0.300 None 1.000 1 1998 1998
CUI: C0751408
Disease: Suffering, Physical
Suffering, Physical
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 0.300 None 1.000 1 1998 1998
CUI: C0234238
Disease: Ache
Ache
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 0.300 None 1.000 1 1998 1998
CUI: C0234230
Disease: Pain, Burning
Pain, Burning
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 0.300 None 1.000 1 1998 1998
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 0.300 None 1.000 1 1998 1998
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
phenotype Chemically-Induced Disorders; Mental Disorders Sign or Symptom 58 0.320 None 1.000 2 1998 2019
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
group Mental Disorders Mental or Behavioral Dysfunction 168 218 0.340 None 1.000 4 2001 2019
CUI: C0178417
Disease: Anhedonia
Anhedonia
disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 24 0.340 None 1.000 1 2011 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
disease Mental Disorders Mental or Behavioral Dysfunction 289 7 0.400 None 1.000 5 2007 2020
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 268 231 0.400 None 0.800 5 2004 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression
disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 254 0.400 None 1.000 5 2007 2020
CUI: C0030193
Disease: Pain
Pain
phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 49 14 0.400 None 0.944 1 1998 2019
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
phenotype Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Disease or Syndrome 25 24 0.500 None 1.000 1 2004 2006
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 139 5 0.550 None 1.000 7 1996 2019