SNCA, synuclein alpha, 6622

N. diseases: 449; N. variants: 66
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C1868595
Disease: PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder) 		disease Disease or Syndrome 1 5 0.900 None 1.000 9 5 1997 2015
CUI: C0865474
Disease: Parkinsonism or Parkinson's disease NOS
Parkinsonism or Parkinson's disease NOS 		disease Disease or Syndrome 1 0.200 None 0
CUI: C0865475
Disease: Idiopathic Parkinsonism or Parkinson's disease
Idiopathic Parkinsonism or Parkinson's disease 		disease Disease or Syndrome 1 0.200 None 0
CUI: C0865476
Disease: Primary Parkinsonism or Parkinson's disease
Primary Parkinsonism or Parkinson's disease 		disease Disease or Syndrome 1 0.200 None 0
CUI: C1854182
Disease: PARKINSON DISEASE 4, AUTOSOMAL DOMINANT LEWY BODY (disorder)
PARKINSON DISEASE 4, AUTOSOMAL DOMINANT LEWY BODY (disorder) 		disease Nervous System Diseases; Mental Disorders Disease or Syndrome 1 0.700 None 0
CUI: C0599458
Disease: glycosphingolipidoses
glycosphingolipidoses 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases Disease or Syndrome 2 0.010 None 1.000 1 2018 2018
CUI: C0154536
Disease: Amphetamine or related acting sympathomimetic abuse
Amphetamine or related acting sympathomimetic abuse 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 3 0.200 None 1.000 1 2010 2010
CUI: C1112261
Disease: Gaze palsy
Gaze palsy 		disease Disease or Syndrome 3 0.010 None 1.000 1 1998 1998
CUI: C1851958
Disease: Lewy Body Variant of Alzheimer Disease
Lewy Body Variant of Alzheimer Disease 		disease Nervous System Diseases; Mental Disorders Disease or Syndrome 4 2 0.020 None 1.000 2 2 2000 2005
CUI: C4477086
Disease: Cotton wool plaques
Cotton wool plaques 		phenotype Pathological Conditions, Signs and Symptoms Acquired Abnormality 4 0.020 None 1.000 2 2003 2005
CUI: C0262424
Disease: CNS DEGENERATION
CNS DEGENERATION 		disease Nervous System Diseases Disease or Syndrome 4 0.010 None 1.000 1 2010 2010
CUI: C1853445
Disease: PARKINSON DISEASE 7, AUTOSOMAL RECESSIVE EARLY-ONSET
PARKINSON DISEASE 7, AUTOSOMAL RECESSIVE EARLY-ONSET 		disease Nervous System Diseases Disease or Syndrome 4 7 0.010 None 1.000 1 2004 2004
CUI: C1399358
Disease: Hemiparkinsonism
Hemiparkinsonism 		disease Disease or Syndrome 4 0.200 None 0
CUI: C1969363
Disease: Middle age onset
Middle age onset 		phenotype Finding 5 0.100 None 0
CUI: C0268250
Disease: Gaucher Disease, Type 2 (disorder)
Gaucher Disease, Type 2 (disorder) 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases Disease or Syndrome 6 34 0.310 None 1.000 2 2009 2016
CUI: C1850442
Disease: CEROID LIPOFUSCINOSIS, NEURONAL, 5
CEROID LIPOFUSCINOSIS, NEURONAL, 5 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases Disease or Syndrome 6 58 0.010 None 1.000 1 2019 2019
CUI: C0270733
Disease: Striatonigral Degeneration
Striatonigral Degeneration 		disease Nervous System Diseases Disease or Syndrome 7 0.020 None 1.000 2 2003 2012
CUI: C0030508
Disease: Parasomnia
Parasomnia 		group Nervous System Diseases; Mental Disorders Disease or Syndrome 7 0.010 None 1.000 1 2018 2018
CUI: C0338473
Disease: Neuroaxonal Dystrophies
Neuroaxonal Dystrophies 		group Nervous System Diseases Disease or Syndrome 7 1 0.010 None 1.000 1 2013 2013
CUI: C1850100
Disease: PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE (disorder)
PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE (disorder) 		disease Eye Diseases; Nervous System Diseases Disease or Syndrome 7 6 0.310 None 1.000 1 1 2013 2013
CUI: C0037019
Disease: Shy-Drager Syndrome
Shy-Drager Syndrome 		disease Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 8 7 0.010 None 1.000 1 2010 2010
CUI: C0729555
Disease: Infection of digestive system
Infection of digestive system 		group Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Infections Disease or Syndrome 8 0.010 None 1.000 1 2017 2017
CUI: C1843792
Disease: FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		disease Disease or Syndrome 8 23 0.010 None 1.000 1 2006 2006
CUI: C0349081
Disease: Dementia in Parkinson's disease
Dementia in Parkinson's disease 		disease Disease or Syndrome 9 2 0.040 None 1.000 4 2007 2012
CUI: C1853833
Disease: Parkinson Disease 6, Autosomal Recessive Early-Onset
Parkinson Disease 6, Autosomal Recessive Early-Onset 		disease Nervous System Diseases Disease or Syndrome 9 25 0.020 None 1.000 2 2017 2019