BTK, Bruton tyrosine kinase, 695

N. diseases: 233; N. variants: 6
Source: BEFREE ×
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0855138
Disease: Mantle cell lymphoma refractory
Mantle cell lymphoma refractory 		disease Neoplastic Process 6 0.030 None 1.000 3 2016 2019
CUI: C2895206
Disease: Autoimmune disease (systemic) NOS
Autoimmune disease (systemic) NOS 		disease Disease or Syndrome 37 3 0.030 None 1.000 3 2016 2019
CUI: C0238790
Disease: bone destruction
bone destruction 		disease Disease or Syndrome 234 3 0.020 None 1.000 2 2019 2019
CUI: C0865214
Disease: Autosomal recessive agammaglobulinemia
Autosomal recessive agammaglobulinemia 		disease Disease or Syndrome 7 0.020 None 1.000 2 2015 2020
CUI: C1333296
Disease: Activated B-cell type diffuse large B-cell lymphoma
Activated B-cell type diffuse large B-cell lymphoma 		disease Neoplastic Process 39 2 0.020 None 1.000 2 2015 2015
CUI: C1740827
Disease: CLL progression
CLL progression 		disease Neoplastic Process 28 2 0.020 None 1.000 2 2015 2019
CUI: C3714796
Disease: Isolated somatotropin deficiency
Isolated somatotropin deficiency 		disease Disease or Syndrome 96 15 0.120 None 1.000 2 1994 2005
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		disease Disease or Syndrome 632 9 0.020 None 1.000 2 2016 2019
CUI: C0398712
Disease: Anti-polysaccharide antibody deficiency
Anti-polysaccharide antibody deficiency 		disease Disease or Syndrome 1 0.010 None 1.000 1 2001 2001
CUI: C0677932
Disease: Progressive Neoplastic Disease
Progressive Neoplastic Disease 		phenotype Neoplastic Process 384 40 0.010 None 1.000 1 2019 2019
CUI: C0746757
Disease: Chronic nasal congestion
Chronic nasal congestion 		disease Disease or Syndrome 1 0.010 None 1.000 1 1997 1997
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		disease Neoplastic Process 860 154 0.010 None 1.000 1 2003 2003
CUI: C0877008
Disease: Enzyme inhibition disorder
Enzyme inhibition disorder 		phenotype Disease or Syndrome 171 1 0.010 None 1.000 1 2017 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		phenotype Neoplastic Process 6626 169 0.010 None 1.000 1 2019 2019
CUI: C1332225
Disease: Aggressive Non-Hodgkin Lymphoma
Aggressive Non-Hodgkin Lymphoma 		disease Neoplastic Process 57 1 0.010 None 1.000 1 2013 2013
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		phenotype Neoplastic Process 1027 20 0.010 None 1.000 1 1998 1998
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		disease Neoplastic Process 346 19 0.010 None 1.000 1 2018 2018
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis 		disease Acquired Abnormality 115 15 0.010 None 1.000 1 2019 2019
CUI: C2347748
Disease: Adult Erythroleukemia
Adult Erythroleukemia 		disease Neoplastic Process 236 4 0.010 None 1.000 1 1994 1994
CUI: C3146250
Disease: Stage III Colorectal Cancer AJCC v7
Stage III Colorectal Cancer AJCC v7 		disease Neoplastic Process 44 3 0.010 None 1.000 1 2019 2019
CUI: C3203655
Disease: Autoimmune aplastic anaemia
Autoimmune aplastic anaemia 		disease Disease or Syndrome 1 0.010 None 1.000 1 2019 2019
CUI: C3275069
Disease: Chronic Total Occlusion Vessel
Chronic Total Occlusion Vessel 		disease Disease or Syndrome 33 0.010 None 1.000 1 2019 2019
CUI: C3539781
Disease: Progressive cGVHD
Progressive cGVHD 		disease Disease or Syndrome 384 40 0.010 None 1.000 1 2019 2019
CUI: C3888789
Disease: Pancreatic toxicity
Pancreatic toxicity 		disease Disease or Syndrome 8 2 0.010 None 1.000 1 2017 2017
CUI: C4087393
Disease: Marginal zone lymphoma refractory
Marginal zone lymphoma refractory 		disease Neoplastic Process 2 0.010 None 1.000 1 2017 2017