TPO, thyroid peroxidase, 7173

N. diseases: 306; N. variants: 47
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C3840565
Disease: Autoimmune thyroid disease (AITD)
Autoimmune thyroid disease (AITD) 		disease Disease or Syndrome 133 54 0.090 None 1.000 9 2 1993 2019
CUI: C1321809
Disease: HYPOTHYROIDISM, GOITROUS
HYPOTHYROIDISM, GOITROUS 		disease Disease or Syndrome 5 2 0.070 None 1.000 7 2 2003 2016
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		disease Neoplastic Process 245 80 0.050 None 1.000 5 2 1995 2013
CUI: C3160718
Disease: PARKINSON DISEASE, LATE-ONSET
PARKINSON DISEASE, LATE-ONSET 		disease Disease or Syndrome 247 76 0.050 None 1.000 5 2017 2018
CUI: C1868193
Disease: PNEUMOTHORAX, PRIMARY SPONTANEOUS
PNEUMOTHORAX, PRIMARY SPONTANEOUS 		disease Disease or Syndrome 46 15 0.030 None 1.000 3 2010 2019
CUI: C0740279
Disease: Cerebellar atrophy
Cerebellar atrophy 		disease Disease or Syndrome 321 67 0.020 None 1.000 2 2017 2017
CUI: C3715197
Disease: Primary congenital hypothyroidism
Primary congenital hypothyroidism 		disease Disease or Syndrome 6 0.020 None 1.000 2 2011 2018
CUI: C4324720
Disease: Autoimmune thyroid disorder
Autoimmune thyroid disorder 		disease Disease or Syndrome 4 0.020 None 1.000 2 2017 2019
CUI: C4329703
Disease: Defective Thyroglobulin Synthesis
Defective Thyroglobulin Synthesis 		disease Disease or Syndrome 2 0.020 None 1.000 2 1990 1991
CUI: C0028259
Disease: Nodule
Nodule 		phenotype Acquired Abnormality 278 19 0.010 None 1.000 1 2019 2019
CUI: C0156841
Disease: Thyroid dysfunction, postpartum
Thyroid dysfunction, postpartum 		disease Disease or Syndrome 2 0.010 None 1.000 1 1998 1998
CUI: C0221505
Disease: Lesion of brain
Lesion of brain 		group Disease or Syndrome 188 9 0.010 None < 0.001 1 2017 2017
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders 		group Mental or Behavioral Dysfunction 360 56 0.010 None 1.000 1 2019 2019
CUI: C0476227
Disease: pricking of skin
pricking of skin 		phenotype Sign or Symptom 65 1 0.010 None 1.000 1 2019 2019
CUI: C0742035
Disease: Cerebellar lesion NOS
Cerebellar lesion NOS 		disease Disease or Syndrome 9 0.010 None < 0.001 1 2017 2017
CUI: C0747845
Disease: early pregnancy
early pregnancy 		phenotype Disease or Syndrome 273 8 0.010 None 1.000 1 2019 2019
CUI: C0749470
Disease: Thyroid cold nodule
Thyroid cold nodule 		disease Disease or Syndrome 1 0.010 None 1.000 1 2001 2001
CUI: C1262091
Disease: Lymphocytic infiltration
Lymphocytic infiltration 		disease Disease or Syndrome 84 2 0.010 None 1.000 1 2018 2018
CUI: C1739405
Disease: CML progression
CML progression 		disease Neoplastic Process 47 3 0.010 None < 0.001 1 2000 2000
CUI: C2750949
Disease: Iodide organification defect
Iodide organification defect 		phenotype Finding 2 0.300 strong 1.000 1 2016 2016
CUI: C3150797
Disease: AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6
AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6 		disease Finding 82 141 0.100 None 1.000 1 1 2019 2019
CUI: C3809874
Disease: LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3
LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3 		disease Neoplastic Process 7 1 0.010 None 1.000 1 2007 2007
CUI: C3827793
Disease: Transient hypothyroxinaemia of prematurity
Transient hypothyroxinaemia of prematurity 		disease Disease or Syndrome 6 0.010 None 1.000 1 2016 2016
CUI: C3887896
Disease: Primary Adrenal Insufficiency
Primary Adrenal Insufficiency 		disease Disease or Syndrome 27 2 0.010 None 1.000 1 1998 1998
CUI: C4014795
Disease: AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1 		disease Disease or Syndrome 82 142 0.100 None 1.000 1 1 2019 2019