TPO, thyroid peroxidase, 7173

N. diseases: 306; N. variants: 47
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C1291299
Disease: Deficiency of iodide peroxidase (disorder)
Deficiency of iodide peroxidase (disorder) 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases Disease or Syndrome 1 27 0.700 strong 1.000 29 27 1992 2016
CUI: C0749470
Disease: Thyroid cold nodule
Thyroid cold nodule 		disease Disease or Syndrome 1 0.010 None 1.000 1 2001 2001
CUI: C4544488
Disease: Neonatal disorder of endocrine system
Neonatal disorder of endocrine system 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases Disease or Syndrome 1 0.010 None 1.000 1 2014 2014
CUI: C1848800
Disease: Thyroid defect in oxidation and organification of iodide
Thyroid defect in oxidation and organification of iodide 		phenotype Finding 1 0.100 None 0
CUI: C4329703
Disease: Defective Thyroglobulin Synthesis
Defective Thyroglobulin Synthesis 		disease Disease or Syndrome 2 0.020 None 1.000 2 1990 1991
CUI: C0156841
Disease: Thyroid dysfunction, postpartum
Thyroid dysfunction, postpartum 		disease Disease or Syndrome 2 0.010 None 1.000 1 1998 1998
CUI: C0342122
Disease: Toxic diffuse goiter
Toxic diffuse goiter 		disease Endocrine System Diseases Disease or Syndrome 2 0.010 None 1.000 1 2001 2001
CUI: C2750949
Disease: Iodide organification defect
Iodide organification defect 		phenotype Finding 2 0.300 strong 1.000 1 2016 2016
CUI: C0027145
Disease: Myxedema
Myxedema 		disease Skin and Connective Tissue Diseases; Endocrine System Diseases Disease or Syndrome 3 0.010 None 1.000 1 1991 1991
CUI: C1578691
Disease: Myxedema, Congenital
Myxedema, Congenital 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases Disease or Syndrome; Congenital Abnormality 4 0.300 None 1.000 4 2003 2007
CUI: C4324720
Disease: Autoimmune thyroid disorder
Autoimmune thyroid disorder 		disease Disease or Syndrome 4 0.020 None 1.000 2 2017 2019
CUI: C0342153
Disease: Congenital thyroid hypoplasia
Congenital thyroid hypoplasia 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases Congenital Abnormality 4 5 0.010 None 1.000 1 2018 2018
CUI: C0854866
Disease: Recurrent Non-Hodgkin Lymphoma
Recurrent Non-Hodgkin Lymphoma 		disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases Neoplastic Process 4 0.010 None 1.000 1 2019 2019
CUI: C4331762
Disease: Wolff-Chaikoff Phenomenon
Wolff-Chaikoff Phenomenon 		disease Endocrine System Diseases Disease or Syndrome 4 0.010 None 1.000 1 1996 1996
CUI: C1321809
Disease: HYPOTHYROIDISM, GOITROUS
HYPOTHYROIDISM, GOITROUS 		disease Disease or Syndrome 5 2 0.070 None 1.000 7 2 2003 2016
CUI: C0271826
Disease: Iodide transport defect
Iodide transport defect 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases Disease or Syndrome 5 2 0.010 None 1.000 1 2014 2014
CUI: C1848805
Disease: Thyroid Dyshormonogenesis 1
Thyroid Dyshormonogenesis 1 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases Disease or Syndrome 6 7 0.310 None 1.000 3 2008 2011
CUI: C3715197
Disease: Primary congenital hypothyroidism
Primary congenital hypothyroidism 		disease Disease or Syndrome 6 0.020 None 1.000 2 2011 2018
CUI: C0271795
Disease: Transient hypothyroidism
Transient hypothyroidism 		disease Pathological Conditions, Signs and Symptoms; Endocrine System Diseases Disease or Syndrome 6 0.010 None 1.000 1 2002 2002
CUI: C1855794
Disease: Bamforth syndrome
Bamforth syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Endocrine System Diseases; Stomatognathic Diseases Disease or Syndrome 6 3 0.010 None 1.000 1 2014 2014
CUI: C3827793
Disease: Transient hypothyroxinaemia of prematurity
Transient hypothyroxinaemia of prematurity 		disease Disease or Syndrome 6 0.010 None 1.000 1 2016 2016
CUI: C0349476
Disease: Congenital goiter
Congenital goiter 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases Disease or Syndrome 7 3 0.080 None 1.000 8 1979 2007
CUI: C3809874
Disease: LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3
LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3 		disease Neoplastic Process 7 1 0.010 None 1.000 1 2007 2007
CUI: C4303761
Disease: Familial thrombocytosis
Familial thrombocytosis 		disease Hemic and Lymphatic Diseases Disease or Syndrome 7 5 0.010 None 1.000 1 2000 2000
CUI: C0001621
Disease: Adrenal Gland Diseases
Adrenal Gland Diseases 		group Endocrine System Diseases Disease or Syndrome 9 2 0.010 None 1.000 1 1999 1999