C5, complement C5, 727

N. diseases: 129; N. variants: 20
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0343713
Disease: Gonococcal arthritis dermatitis syndrome
Gonococcal arthritis dermatitis syndrome 		disease Infections; Skin and Connective Tissue Diseases; Musculoskeletal Diseases Disease or Syndrome 1 0.010 None 1.000 1 1981 1981
CUI: C0744451
Disease: Disseminated infection caused by Neisseria gonorrhoeae
Disseminated infection caused by Neisseria gonorrhoeae 		disease Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases Disease or Syndrome 1 0.010 None 1.000 1 1979 1979
CUI: C3810402
Disease: ECULIZUMAB, POOR RESPONSE TO
ECULIZUMAB, POOR RESPONSE TO 		disease Disease or Syndrome 1 2 0.100 None 0 2
CUI: C4024844
Disease: Generalized seborrheic dermatitis
Generalized seborrheic dermatitis 		disease Skin and Connective Tissue Diseases Disease or Syndrome 1 0.100 None 0
CUI: C0851883
Disease: Neisseria infection
Neisseria infection 		disease Infections Disease or Syndrome 2 0.010 None 1.000 1 1981 1981
CUI: C0343047
Disease: Complement component 5 deficiency
Complement component 5 deficiency 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases Disease or Syndrome 3 5 0.610 strong 1.000 2 5 1977 2015
CUI: C1449646
Disease: Primary Peritonitis
Primary Peritonitis 		disease Digestive System Diseases; Infections Disease or Syndrome 3 0.300 None 1.000 2 2009 2009
CUI: C0746495
Disease: Recurrent meningitis
Recurrent meningitis 		disease Infections; Nervous System Diseases Disease or Syndrome 6 2 0.100 None 0
CUI: C1449647
Disease: Secondary Peritonitis
Secondary Peritonitis 		disease Digestive System Diseases; Infections Disease or Syndrome 8 0.300 None 1.000 2 2009 2009
CUI: C0231818
Disease: Airway constriction
Airway constriction 		phenotype Sign or Symptom 8 0.010 None 1.000 1 2017 2017
CUI: C0020951
Disease: Immune Complex Diseases
Immune Complex Diseases 		group Immune System Diseases Disease or Syndrome 10 0.010 None 1.000 1 1999 1999
CUI: C0003907
Disease: Arthus Reaction
Arthus Reaction 		disease Immune System Diseases Disease or Syndrome 12 0.010 None 1.000 1 1999 1999
CUI: C0743178
Disease: Intractable diarrhea
Intractable diarrhea 		disease Pathological Conditions, Signs and Symptoms Disease or Syndrome 13 3 0.100 None 0
CUI: C0031154
Disease: Peritonitis
Peritonitis 		disease Digestive System Diseases; Infections Pathologic Function 15 2 0.300 None 1.000 2 2009 2009
CUI: C0025294
Disease: Meningococcal meningitis
Meningococcal meningitis 		disease Infections; Nervous System Diseases Disease or Syndrome 17 3 0.010 None 1.000 1 1981 1981
CUI: C0025306
Disease: Meningococcemia
Meningococcemia 		disease Infections Disease or Syndrome 20 0.020 None 1.000 2 1981 2018
CUI: C0003257
Disease: Antibody Deficiency Syndrome
Antibody Deficiency Syndrome 		disease Immune System Diseases Disease or Syndrome 21 0.300 None 1.000 1 1995 1995
CUI: C1527311
Disease: Brain Edema
Brain Edema 		phenotype Nervous System Diseases Pathologic Function 30 0.200 None 1.000 1 2001 2001
CUI: C0025048
Disease: Meconium Aspiration Syndrome
Meconium Aspiration Syndrome 		phenotype Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Respiratory Tract Diseases Disease or Syndrome 38 1 0.010 None 1.000 1 2018 2018
CUI: C0272242
Disease: Complement deficiency disease
Complement deficiency disease 		group Immune System Diseases; Hemic and Lymphatic Diseases Disease or Syndrome 42 0.400 strong 1.000 1 2015 2015
CUI: C2931788
Disease: Atypical Hemolytic Uremic Syndrome
Atypical Hemolytic Uremic Syndrome 		disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Hemic and Lymphatic Diseases Disease or Syndrome 56 42 0.060 None 1.000 6 2014 2019
CUI: C0302809
Disease: Fulminant hepatitis
Fulminant hepatitis 		disease Digestive System Diseases Disease or Syndrome 57 1 0.010 None 1.000 1 2018 2018
CUI: C1260959
Disease: Drusen
Drusen 		disease Disease or Syndrome 57 18 0.010 None < 0.001 1 2010 2010
CUI: C2717961
Disease: Thrombotic Microangiopathies
Thrombotic Microangiopathies 		group Hemic and Lymphatic Diseases Disease or Syndrome 62 8 0.020 None 1.000 2 2011 2017
CUI: C0016412
Disease: Folic Acid Deficiency
Folic Acid Deficiency 		disease Nutritional and Metabolic Diseases Disease or Syndrome 70 8 0.010 None 1.000 1 2013 2013