Spastic Paraplegia 42, Autosomal Dominant
|
disease |
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
|
Disease or Syndrome
|
1
|
1
|
0.710 |
None |
1.000 |
3 |
1
|
2008 |
2018 |
CONGENITAL CATARACTS, HEARING LOSS, AND NEURODEGENERATION
|
disease |
|
Disease or Syndrome
|
1
|
2
|
0.700 |
None |
1.000 |
3 |
2
|
2012 |
2018 |
Spinal cord lesion
|
phenotype |
Nervous System Diseases
|
Finding
|
7
|
|
0.100 |
None |
|
0 |
|
|
|
Megaureter
|
disease |
|
Congenital Abnormality
|
8
|
|
0.010 |
None |
1.000 |
1 |
|
1999 |
1999 |
Progressive pes cavus
|
phenotype |
|
Finding
|
9
|
|
0.100 |
None |
|
0 |
|
|
|
Decreased serum ceruloplasmin
|
phenotype |
|
Finding
|
12
|
5
|
0.100 |
None |
|
0 |
|
|
|
Spastic paraplegia 10, autosomal dominant
|
disease |
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
|
Disease or Syndrome
|
16
|
10
|
0.010 |
None |
1.000 |
1 |
|
2008 |
2008 |
BESTROPHINOPATHY, AUTOSOMAL RECESSIVE
|
disease |
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
|
Disease or Syndrome
|
17
|
32
|
0.010 |
None |
1.000 |
1 |
|
2018 |
2018 |
Lower limb amyotrophy
|
phenotype |
|
Finding
|
19
|
4
|
0.100 |
None |
|
0 |
|
|
|
Lower limb hypertonia
|
phenotype |
|
Finding
|
21
|
5
|
0.100 |
None |
|
0 |
|
|
|
Degeneration of the lateral corticospinal tracts
|
phenotype |
|
Finding
|
21
|
|
0.100 |
None |
|
0 |
|
|
|
Secondary hypertension
|
disease |
Cardiovascular Diseases
|
Disease or Syndrome
|
22
|
1
|
0.010 |
None |
1.000 |
1 |
|
1994 |
1994 |
Malignant Hypertension
|
disease |
Cardiovascular Diseases
|
Disease or Syndrome
|
23
|
2
|
0.010 |
None |
1.000 |
1 |
|
2011 |
2011 |
Lens Opacities
|
phenotype |
Eye Diseases
|
Finding
|
24
|
|
0.300 |
None |
1.000 |
1 |
|
2012 |
2012 |
Congenital posterior urethral valves
|
disease |
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
|
Congenital Abnormality
|
26
|
1
|
0.010 |
None |
1.000 |
1 |
|
1999 |
1999 |
Pseudoaphakia
|
disease |
Eye Diseases
|
Disease or Syndrome
|
28
|
|
0.300 |
None |
1.000 |
1 |
|
2012 |
2012 |
Right ventricular failure
|
disease |
Cardiovascular Diseases
|
Disease or Syndrome
|
28
|
|
0.010 |
None |
1.000 |
1 |
|
2018 |
2018 |
Child Development Deviations
|
disease |
Mental Disorders
|
Mental or Behavioral Dysfunction
|
29
|
|
0.300 |
None |
1.000 |
1 |
|
2012 |
2012 |
Child Development Disorders, Specific
|
disease |
Mental Disorders
|
Mental or Behavioral Dysfunction
|
30
|
|
0.300 |
None |
1.000 |
1 |
|
2012 |
2012 |
Hypertensive heart disease
|
disease |
Cardiovascular Diseases
|
Disease or Syndrome
|
32
|
|
0.010 |
None |
1.000 |
1 |
|
2003 |
2003 |
CNS hypomyelination
|
phenotype |
|
Finding
|
32
|
6
|
0.100 |
None |
|
0 |
|
|
|
Lower limb hyperreflexia
|
phenotype |
Pathological Conditions, Signs and Symptoms; Nervous System Diseases
|
Finding
|
38
|
6
|
0.100 |
None |
|
0 |
|
|
|
Impaired vibration sensation in the lower limbs
|
phenotype |
|
Finding
|
39
|
4
|
0.100 |
None |
|
0 |
|
|
|
Vesicoureteral Reflux 1
|
disease |
Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
|
Disease or Syndrome
|
47
|
10
|
0.020 |
None |
1.000 |
2 |
|
1999 |
2002 |
Cognitive changes
|
phenotype |
Pathological Conditions, Signs and Symptoms; Nervous System Diseases
|
Mental or Behavioral Dysfunction
|
50
|
15
|
0.010 |
None |
1.000 |
1 |
|
2019 |
2019 |