ABI1, abl interactor 1, 10006

N. diseases: 56; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 Biomarker phenotype BEFREE To investigate the molecular mechanism by which loss of ABI1 contributes to tumor progression, we disrupted the ABI1 gene in the benign prostate epithelial RWPE-1 cell line and determined its phenotype. 31530281 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 Biomarker phenotype BEFREE Because of its role in cell migration, Abi1 has been implicated in tumor progression. 26193797 2015
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 AlteredExpression phenotype BEFREE Down-regulation of E3B1/ABI-1 expression in human carcinomas may play a critical role in tumor progression and in determining disease prognosis. 22430194 2012
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 AlteredExpression phenotype BEFREE The expression of ABI1 and its role in cancer progression and prognosis are largely unknown in the majority of solid tumors, including gastric cancer. 19554484 2010