Malignant Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Therefore, lncRNA MORT was downregulated in ovarian carcinoma and lncRNA MORT overexpression inhibited cancer cell proliferation, possibly by downregulating miRNA-21.
|
30916806 |
2019 |
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
However, overexpression of lncRNA MORT showed no significant effects on cancer cell migration and invasion.
|
30916806 |
2019 |
Tumor Cell Invasion
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
Overexpression of ZNF667-AS1 reduced the proliferation, migration, and invasion ability of AMC-HN-8 and TU177 cells.
|
30684967 |
2019 |
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
MiR-93-3p inhibition and ZNF667-AS1 elevation also inhibited cell cycle entry and cell invasion in vitro, but repressed tumor growth and metastasis in vivo.
|
31420931 |
2019 |
Primary malignant neoplasm
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Therefore, lncRNA MORT was downregulated in ovarian carcinoma and lncRNA MORT overexpression inhibited cancer cell proliferation, possibly by downregulating miRNA-21.
|
30916806 |
2019 |
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
Therefore, lncRNA MORT may inhibit cancer cell proliferation in prostate carcinoma by preventing glucose uptake.
|
31516590 |
2019 |
Primary malignant neoplasm
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Therefore, lncRNA MORT overexpression may inhibit cancer cell proliferation in OSCC cells by downregulating ROCK1.
|
30805944 |
2019 |
Malignant tumor of cervix
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
MiR-93-3p was found to be highly expressed, while ZNF667-AS1 and PEG3 were poorly expressed in CC.
|
31420931 |
2019 |
Neoplasm Metastasis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
MiR-93-3p inhibition and ZNF667-AS1 elevation also inhibited cell cycle entry and cell invasion in vitro, but repressed tumor growth and metastasis in vivo.
|
31420931 |
2019 |
Neoplasm Metastasis
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
Expression of lncRNA MORT in tumor tissues was found to be significantly affected by tumor size but not by tumor metastasis.
|
30916806 |
2019 |
Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Expression of lncRNA MORT in tumor tissues was found to be significantly affected by tumor size but not by tumor metastasis.
|
30916806 |
2019 |
Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Expression of lncRNA MORT in tumor tissues was influenced by tumor size, but not by tumor metastasis.
|
31516590 |
2019 |
Cervix carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
MiR-93-3p was found to be highly expressed, while ZNF667-AS1 and PEG3 were poorly expressed in CC.
|
31420931 |
2019 |
Carcinogenesis
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
Herein, we aimed to analyze the interactions between ZNF667-AS1, microRNA-93-3p (miR-93-3p), and paternally expressed gene 3 (PEG3) and to explore their roles in the tumorigenesis of cervical cancer (CC).
|
31420931 |
2019 |
Malignant tumor of cervix
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The results showed that the expression of LncRNA ZNF667-AS1 in cervical cancer was significantly lower than that in normal cervical tissues.
|
29243775 |
2017 |
Cervix carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The results showed that the expression of LncRNA ZNF667-AS1 in cervical cancer was significantly lower than that in normal cervical tissues.
|
29243775 |
2017 |
Carcinogenesis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
The epigenetic silencing of MORT in a large majority of the common human cancers suggests a potential fundamental role in cellular immortalization during human carcinogenesis.
|
26646903 |
2015 |
Squamous cell carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Long noncoding RNA MORT overexpression inhibits cancer cell proliferation in oral squamous cell carcinoma by downregulating ROCK1.
|
30805944 |
2019 |
Periodontitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
MORT is involved in the proliferation of human PDLSCs and affects the recurrence of periodontitis.
|
31195182 |
2019 |
Esophageal carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The expression levels of ZNF667-AS1 and ZNF667 were significantly reversed by treatment with 5-Aza-dC and TSA in esophageal cancer cell lines.
|
31804468 |
2019 |
Squamous cell carcinoma of esophagus
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study was to investigate the expression patterns, epigenetic inactivation mechanisms, function, and prognostic significance of ZNF667-AS1 and ZNF667 in ESCC tumorigenesis.
|
31804468 |
2019 |
Laryngeal Squamous Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Aberrant methylation and downregulation of ZNF667-AS1 and ZNF667 promote the malignant progression of laryngeal squamous cell carcinoma.
|
30684967 |
2019 |
Prostate carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Therefore, lncRNA MORT may inhibit cancer cell proliferation in prostate carcinoma by preventing glucose uptake.
|
31516590 |
2019 |
Secondary Neoplasm
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Expression of lncRNA MORT in tumor tissues was found to be significantly affected by tumor size but not by tumor metastasis.
|
30916806 |
2019 |