Coronary heart disease
|
0.050 |
Biomarker
|
disease |
BEFREE |
Kinesin-like protein 6 (KIF6) is a new candidate gene for CHD, since it has been identified as a potential risk factor.
|
28096762 |
2015 |
Coronary heart disease
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials.
|
18222353 |
2008 |
Coronary heart disease
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease.
|
21435211 |
2011 |
Coronary heart disease
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.
|
20933357 |
2010 |
Coronary heart disease
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNPs) at the KIF6 (kinesin like protein 6, rs20455 or 719Arg), LPA (lipoprotein(a), rs3798220), TAS2R50 (taste receptor type 2, member 50, rs1376251) and VAMP8 (vesicle-associated membrane protein 8, rs1010) have previously been associated with low density lipoprotein cholesterol (LDL-C) lowering response to statins, coronary heart disease (CHD) at baseline, or CHD events on trial.
|
22192511 |
2012 |
Coronary Artery Disease
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.
|
20933357 |
2010 |
Coronary Artery Disease
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease.
|
21435211 |
2011 |
Coronary Artery Disease
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
A single-nucleotide polymorphism Trp719Arg (rs20455T>C) in the kinesin-like protein 6 (KIF6), which is a protein involved in intracellular transport, has been shown to predict increased coronary artery disease (CAD) risk and event reduction during statin therapy.
|
21810021 |
2011 |
Coronary Artery Disease
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials.
|
18222353 |
2008 |
Coronary Arteriosclerosis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.
|
20933357 |
2010 |
Coronary Arteriosclerosis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials.
|
18222353 |
2008 |
Coronary Arteriosclerosis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease.
|
21435211 |
2011 |
Diabetes
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and cardiovascular risk and efficacy of atorvastatin among subjects with diabetes on dialysis: the 4D study.
|
21871624 |
2011 |
Myocardial Infarction
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials.
|
18222353 |
2008 |
Diabetes Mellitus
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and cardiovascular risk and efficacy of atorvastatin among subjects with diabetes on dialysis: the 4D study.
|
21871624 |
2011 |