Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.
|
30575882 |
2018 |
Malignant neoplasm of breast
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
We show that a global or vascular endothelial cell (EC)-specific deletion of the AIP1 gene in mice augments tumor growth and metastasis in melanoma and breast cancer models.
|
26139244 |
2015 |
Malignant neoplasm of breast
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Also, the PDCD6IP I allele significantly decreased the risk of BC (OR = 0.59, 95% CI = 0.45-0.78, p < 0.001) compared to the D allele.
|
26063962 |
2015 |
Breast Carcinoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Also, the PDCD6IP I allele significantly decreased the risk of BC (OR = 0.59, 95% CI = 0.45-0.78, p < 0.001) compared to the D allele.
|
26063962 |
2015 |
Breast Carcinoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
We show that a global or vascular endothelial cell (EC)-specific deletion of the AIP1 gene in mice augments tumor growth and metastasis in melanoma and breast cancer models.
|
26139244 |
2015 |
Amyloidosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
By screening a peptoid library using surface plasmon resonance imaging, amyloid inhibitory peptoid 1 (AIP1) that has high affinity to Aβ42 is identified.
|
27714968 |
2017 |
Non-Small Cell Lung Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Compared to TNM stage I + II, PDCD6IP I/D polymorphism significantly increased advanced NSCLC risk (OR = 2.06, 95 % CI 1.30-3.26, P < 0.01).
|
24870593 |
2014 |
melanoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We show that a global or vascular endothelial cell (EC)-specific deletion of the AIP1 gene in mice augments tumor growth and metastasis in melanoma and breast cancer models.
|
26139244 |
2015 |
Neoplasm Metastasis
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
We show that a global or vascular endothelial cell (EC)-specific deletion of the AIP1 gene in mice augments tumor growth and metastasis in melanoma and breast cancer models.
|
26139244 |
2015 |
West Syndrome
|
0.010 |
GeneticVariation
|
disease |
LHGDN |
Infantile spasms is associated with deletion of the MAGI2 gene on chromosome 7q11.23-q21.11.
|
18565486 |
2008 |
Malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A common genetic variant (97906C>A) of DAB2IP/AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males.
|
22046421 |
2011 |
Carcinoma of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A common genetic variant (97906C>A) of DAB2IP/AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males.
|
22046421 |
2011 |
Primary malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A common genetic variant (97906C>A) of DAB2IP/AIP1 is associated with an increased risk and early onset of lung cancer in Chinese males.
|
22046421 |
2011 |
Columnar Cell Change of the Breast
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Finally, 3 patients with AIP1 were diagnosed with cholangiocellular carcinoma (CCC).<i>Conclusion</i>.
|
28348580 |
2017 |
Liver carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Taken together, our data suggest that common genetic variations in PDCD6IP may influence HCC risk, possibly through promoter activity-mediated regulation.
|
23777424 |
2013 |
Degenerative polyarthritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance.
|
18784066 |
2009 |
Osteoarthrosis Deformans
|
0.300 |
Biomarker
|
disease |
CTD_human |
Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance.
|
18784066 |
2009 |
Arteriosclerosis
|
0.050 |
Biomarker
|
disease |
BEFREE |
AIP1-mediated stress signaling in atherosclerosis and arteriosclerosis.
|
25732743 |
2015 |
Arteriosclerosis
|
0.050 |
Biomarker
|
disease |
BEFREE |
AIP1 Suppresses Transplant Arteriosclerosis Through Inhibition of Vascular Smooth Muscle Cell Inflammatory Response to IFNγ.
|
30471213 |
2019 |
Arteriosclerosis
|
0.050 |
Biomarker
|
disease |
BEFREE |
AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansion.
|
21700930 |
2011 |
Arteriosclerosis
|
0.050 |
Biomarker
|
disease |
BEFREE |
Approach and Results: We detected a normal AIP1 form (named AIP1A) in the healthy aorta, but a shorter form of AIP1 (named AIP1B) was found in diseased aortae that contained atherosclerotic plaques and graft arteriosclerosis.
|
31619063 |
2020 |
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
These ALIX-positive particles were seen in the tumor nests, including tumor-stroma border, which suggest their exosome function.
|
27150162 |
2016 |
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
An inverse association between ALIX and PD-L1 expression was observed in human breast cancer tissues, while an immunocompetent mouse model of breast cancer revealed that ALIX-deficient tumors are larger and show an increased immunosuppressive environment.
|
30021161 |
2018 |
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
However, the role of AIP1 in the tumor microenvironment has not been examined.
|
26139244 |
2015 |