Urinary tract infection
|
0.010 |
Biomarker
|
group |
BEFREE |
AFA-I may be exemplary of an adhesin class significant for the pathogenesis of human urinary tract infections.
|
2865133 |
1985 |
Recurrent urinary tract infection
|
0.010 |
Biomarker
|
disease |
BEFREE |
AFA-I may be exemplary of an adhesin class significant for the pathogenesis of human urinary tract infections.
|
2865133 |
1985 |
Tuberculosis
|
0.020 |
Biomarker
|
disease |
BEFREE |
A 240 bp region (nts 460-700) from the MPB 64 protein coding gene specific for Mycobacterium tuberculosis (TB) was selected for amplification.Nineteen clinical samples were studied.
|
7899891 |
1994 |
Tuberculosis, extrapulmonary
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Application of nested polymerase chain reaction (nPCR) using MPB 64 gene primers to detect Mycobacterium tuberculosis DNA in clinical specimens from extrapulmonary tuberculosis patients.
|
16177475 |
2005 |
MRSA - Methicillin resistant Staphylococcus aureus infection
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here, we report that MPB, a novel berberine derivative, induced lysosome-based degradation and clearance of methicillin-resistant Staphylococcus aureus and enteroinvasive Escherichia coli in macrophages.
|
30161000 |
2019 |
Coronary heart disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In contrast, the MPB genetic risk score did not show any association with CHD or CHD risk factors.
|
31743359 |
2019 |
Multiple Sclerosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In MS, several reports have suggested that restricted T-cell populations respond to MPB, as in inbred rodents with the MS disease model experimental allergic encephalomyelitis.
|
7689820 |
1993 |
Encephalomyelitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
In MS, several reports have suggested that restricted T-cell populations respond to MPB, as in inbred rodents with the MS disease model experimental allergic encephalomyelitis.
|
7689820 |
1993 |
Tuberculosis
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
In order to find a sensitive and rapid technique nested polymerase chain reaction (nPCR) targeting the conserved MPB 64 gene of Mycobacterium tuberculosis was evaluated for detection of M. tuberculosis DNA directly from clinical specimens of extrapulmonary origin.
|
16177475 |
2005 |
Malignant neoplasm of breast
|
0.010 |
Biomarker
|
disease |
BEFREE |
Some top DEP-responsive genes are novel for breast cancer mortality, such as ABHD14B [for high-vs-low expression, HR 0.36, 95% CI: 0.2-0.5] and TMC4 [HR 0.37, 95% CI: 0.3-0.5]; top hits for MPB (SLC40A1 [HR 0.37, 95% CI: 0.3-0.5] and NTN4 [HR 0.39, 95% CI: 0.3-0.6]) are well-known predictors of breast cancer survival.
|
31593922 |
2019 |
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Some top DEP-responsive genes are novel for breast cancer mortality, such as ABHD14B [for high-vs-low expression, HR 0.36, 95% CI: 0.2-0.5] and TMC4 [HR 0.37, 95% CI: 0.3-0.5]; top hits for MPB (SLC40A1 [HR 0.37, 95% CI: 0.3-0.5] and NTN4 [HR 0.39, 95% CI: 0.3-0.6]) are well-known predictors of breast cancer survival.
|
31593922 |
2019 |
Endocrine System Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
The second most common alopecia-Androgenetic alopecia (AGA)-occurs due to hormonal imbalance.
|
30980598 |
2019 |
Tumor Cell Invasion
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Transfection of afa-1 into E coli K-12 predictably conferred diffuse adherence plus invasion of HEp-2 and I-407 epithelial cells, and upregulation of vascular endothelial growth factor.
|
23846483 |
2014 |
Colorectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
We used a nested case-control study of 238 study subjects to explore the use of microbial markers for clbA+ bacteria harboring the pks pathogenicity island, afa-C+ diffusely adherent Escherichia coli harboring the afa-1 operon, and Fusobacterium nucleatum in stool as potential screening markers for CRC.
|
28833079 |
2017 |
prostatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
With the exception of pil and afaI, all VFs were significantly more often associated with prostatitis, pyelonephritis and cystitis isolates than with the fecal isolates.
|
9255669 |
1997 |
Cystitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
With the exception of pil and afaI, all VFs were significantly more often associated with prostatitis, pyelonephritis and cystitis isolates than with the fecal isolates.
|
9255669 |
1997 |
Infective cystitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
With the exception of pil and afaI, all VFs were significantly more often associated with prostatitis, pyelonephritis and cystitis isolates than with the fecal isolates.
|
9255669 |
1997 |