Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
The presence of 1p abnormalities in AML and other malignancies is reviewed, as are candidate tumor suppressor genes in the 1p34 approximately p36 region.
|
12547161 |
2002 |
Neoplasms
|
0.050 |
GeneticVariation
|
group |
BEFREE |
The p36 region of chromosome one has been reported to have frequent loss of heterozygosity (LOH) in brain and central nervous system (CNS) tumors and epidemiological studies have shown an increased relative risk of BC and tumors of the CNS in PC families.
|
11536309 |
2001 |
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Loss of heterozygosity (LOH) involving the distal chromosome 1 p36 region occurs frequently in nonastrocytic brain tumours, but the tumour suppressor gene targeted by this deletion is unknown. p73 is a novel gene that has high sequence homology and similar gene structure to the p53 gene; it has been mapped to 1 p36, and may thus represent a candidate for this tumour suppressor gene.
|
11461077 |
2001 |
Neoplasms
|
0.050 |
GeneticVariation
|
group |
BEFREE |
LOH at 1 p36 retained independent prognostic significance in a multivariate model that included KIT mutation status and tumor size; the mitotic index, however, did not retain independent significance in such a model.
|
10616197 |
1999 |
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Cytogenetic and molecular studies in neuroblastoma suggest the presence of a tumor suppressor gene at the distal band p36 of human chromosome 1.
|
7700633 |
1995 |
Malaria
|
0.020 |
Biomarker
|
disease |
BEFREE |
A protein called P36 holds the key to how different species of malaria parasite invade liver cells.
|
28614050 |
2017 |
Malaria
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The proteins P52 and P36 are expressed in the sporozoite stage of the murine malaria parasite Plasmodium berghei.
|
23227206 |
2012 |
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
The presence of 1p abnormalities in AML and other malignancies is reviewed, as are candidate tumor suppressor genes in the 1p34 approximately p36 region.
|
12547161 |
2002 |
Brain Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Loss of heterozygosity (LOH) involving the distal chromosome 1 p36 region occurs frequently in nonastrocytic brain tumours, but the tumour suppressor gene targeted by this deletion is unknown. p73 is a novel gene that has high sequence homology and similar gene structure to the p53 gene; it has been mapped to 1 p36, and may thus represent a candidate for this tumour suppressor gene.
|
11461077 |
2001 |
Brain Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
The p36 region of chromosome one has been reported to have frequent loss of heterozygosity (LOH) in brain and central nervous system (CNS) tumors and epidemiological studies have shown an increased relative risk of BC and tumors of the CNS in PC families.
|
11536309 |
2001 |
Malignant Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Southern analysis of cancer DNA showed no noticeable deletion in p36 gene.
|
11522620 |
2001 |
Crohn Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
The reactivity of anti-M. paratuberculosis (specifically against p35 and p36 antigens) antibodies in a significant proportion of CD patients would suggest a causal role for the organism in CD.
|
11118734 |
2000 |
Paratuberculosis
|
0.020 |
Biomarker
|
disease |
BEFREE |
Specific seroreactivity of Crohn's disease patients against p35 and p36 antigens of M. avium subsp. paratuberculosis.
|
11118734 |
2000 |
Crohn Disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
The fact that sera from Crohn's disease patients reacted to p36 with the same high frequency as the sera from patients that were exposed to mycobacterial antigens further supports the hypothesis of the mycobacterial etiology in Crohn's disease.
|
10398839 |
1999 |
Neuroblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
LOH at 1p36 was found in 24 of 80 cases, suggesting the possibility of a tumor suppressor gene at 1 p36 near the site of a suspected neuroblastoma tumor suppressor gene.
|
10616197 |
1999 |
Paratuberculosis
|
0.020 |
Biomarker
|
disease |
BEFREE |
Characterization of Mycobacterium paratuberculosis p36 antigen and its seroreactivities in Crohn's disease.
|
10398839 |
1999 |
Central neuroblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
LOH at 1p36 was found in 24 of 80 cases, suggesting the possibility of a tumor suppressor gene at 1 p36 near the site of a suspected neuroblastoma tumor suppressor gene.
|
10616197 |
1999 |
Childhood Neuroblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
LOH at 1p36 was found in 24 of 80 cases, suggesting the possibility of a tumor suppressor gene at 1 p36 near the site of a suspected neuroblastoma tumor suppressor gene.
|
10616197 |
1999 |
Neuroblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cytogenetic and molecular studies in neuroblastoma suggest the presence of a tumor suppressor gene at the distal band p36 of human chromosome 1.
|
7700633 |
1995 |
Central neuroblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cytogenetic and molecular studies in neuroblastoma suggest the presence of a tumor suppressor gene at the distal band p36 of human chromosome 1.
|
7700633 |
1995 |
Liver carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
These investigations explored the effect of ethanol additions on the expression and tyrosyl phosphorylation (TP) of p36 and IRS-1 in a human hepatocellular carcinoma cell line (FOCUS) in relationship to cell proliferation induced by IN and serum growth factor stimulation.
|
7542850 |
1995 |
Childhood Neuroblastoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cytogenetic and molecular studies in neuroblastoma suggest the presence of a tumor suppressor gene at the distal band p36 of human chromosome 1.
|
7700633 |
1995 |
Liver carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
A 960-base-pair cDNA was isolated and found to be a partial cDNA encoding the human protein-tyrosine kinase substrate p36, also known as lipocortin II. p36 expression was highly abundant in hepatocellular carcinomas at both the transcript and protein levels.
|
2160596 |
1990 |
Tumor Cell Invasion
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Our results support a model in which the putatively glycosylphosphatidylinositol (GPI)-anchored P52 may serve as a scaffold to facilitate the interaction of secreted P36 with the host cell during sporozoite invasion of hepatocytes.
|
30547015 |
2018 |
Harlequin Fetus
|
0.010 |
Biomarker
|
disease |
BEFREE |
In female mice, HI injury prolonged the time spent at the periphery (open field) at p36 (p = 0.004), regardless of treatment.
|
28196356 |
2017 |