Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.060 Biomarker disease BEFREE However, the role of HOTTIP in pancreatic cancer stem cells (PCSCs) remains unclear. 28947139 2017
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.060 GeneticVariation disease BEFREE The current findings provided evidence that the functional rs1859168 A > C polymorphism may decrease the PC risk by down-regulating the HOTTIP expression. 28818070 2017
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.060 AlteredExpression disease BEFREE HOTTIP expression was higher in human pancreatic cancer tissue compared with in para-carcinoma tissue. 30008887 2018
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.060 GeneticVariation disease BEFREE The expression patterns of HOTTIP splice variants in PC were also detected. 26447755 2015
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.060 Biomarker disease BEFREE The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration. 25912306 2015
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.060 Biomarker disease BEFREE A long non-coding RNA named HOXA transcript at the distal tip (HOTTIP) has been reported to be significantly increased in several cancers, including hepatocellular cancer, pancreatic cancer and lung cancer. 28693275 2017