Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029182
Disease: orbit (eye disorders)
orbit (eye disorders)
0.010 Biomarker group BEFREE HAS-BLED is a balanced bleeding risk assessment tool in terms of sensitivity and specificity, whereas the European score, ABC, and mOBRI are high sensitivity tools and ORBIT, ATRIA, Shireman, and GARFIELD-AF are high specificity tools. 31782613 2020
CUI: C0039103
Disease: Synovitis
Synovitis
0.010 Biomarker disease BEFREE A clinical, non-randomized, open label comparison of ACS vs PRP in knee OA with sub-clinical or moderate synovitis symptomology was performed. 31847701 2020
CUI: C0751212
Disease: Hyperalgesia, Secondary
Hyperalgesia, Secondary
0.010 Biomarker phenotype BEFREE The sizes of the effect on pain induced by intradermal injection of capsaicin were quantified by calculating Cohen's d. While in four of the seven pain-related parameters, pregabalin provided a small effect judged by values of Cohen's d exceeding 0.2, an item categorization technique implemented as computed ABC analysis identified the pain intensities in the area of secondary hyperalgesia and of allodynia as the most suitable parameters to quantify the analgesic effects of pregabalin. 31608551 2020
CUI: C0003862
Disease: Arthralgia
Arthralgia
0.010 Biomarker phenotype BEFREE Although the degree of scientific evidence of the publications on intra-articular injections of various drugs (hyaluronic acid, corticosteriods, PRP and MSCs) in haemophilia is very low, it seems that intra-articular injections of hyaluronic acid can relieve joint pain for months and can be repeated every 6-12 months, which is why they can be recommended. 31639263 2019
CUI: C0013274
Disease: Patent ductus arteriosus
Patent ductus arteriosus
0.010 Biomarker disease BEFREE Among the children who completed the K-ABC test, there were no significant differences in neurodevelopmental scores between a closed ductus group (n = 44) and a persistent patent ductus arteriosus group (n = 17). 31708567 2019
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia
0.010 GeneticVariation disease BEFREE Rethinking the criteria for fibromyalgia in 2019: the ABC indicators. 31372029 2019
CUI: C0016667
Disease: Fragile X Syndrome
Fragile X Syndrome
0.010 Biomarker disease BEFREE There was a statistically significant reduction in ADAMS total score from screening to week 12 and significant reductions on nearly all other secondary endpoints, including all ADAMS subscales (except depressed mood), all ABC-C<sub>FXS</sub> subscale scores (e.g., social avoidance, irritability), PARS-R total severity score, and PedsQL total score. 31370779 2019
CUI: C0017601
Disease: Glaucoma
Glaucoma
0.010 Biomarker disease BEFREE Intracameral platelet-rich plasma (E-PRP) injection was an effective, rapidly effective, and safe procedure for treatment of severe chronic ocular hypotony following glaucoma filtrating surgery. 30295074 2019
CUI: C0017609
Disease: Glaucoma, Neovascular
Glaucoma, Neovascular
0.010 Biomarker disease BEFREE This multicenter study indicates that younger age, uncontrolled diabetes, no PRP, and postoperative VH are risk factors of post-vitrectomy NVG. 31619708 2019
CUI: C0019069
Disease: Hemophilia A
Hemophilia A
0.010 Biomarker disease BEFREE Although the degree of scientific evidence of the publications on intra-articular injections of various drugs (hyaluronic acid, corticosteriods, PRP and MSCs) in haemophilia is very low, it seems that intra-articular injections of hyaluronic acid can relieve joint pain for months and can be repeated every 6-12 months, which is why they can be recommended. 31639263 2019
CUI: C0023418
Disease: leukemia
leukemia
0.010 GeneticVariation disease BEFREE The following Mesh terms were used as: "ATP-binding cassette transporters" OR "ABC-transporters*" AND "gene expression*" AND "leukemia" OR "ALL" OR "AML" OR "acute leukemia*". 30860475 2019
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia
0.010 AlteredExpression disease BEFREE Acute lymphoblastic leukemia (ALL) is the most prevalent cancer among children, and multidrug efflux mediated by overexpression of ABC transporters is the major impediment to successful chemotherapy in this malignancy. 30639603 2019
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease
0.010 Biomarker disease BEFREE We use a motivating example, the ABC Index for burden of disease in chronic obstructive pulmonary disease (COPD). 31142198 2019
CUI: C0025289
Disease: Meningitis
Meningitis
0.010 Biomarker disease BEFREE No reliable and comprehensive study has been published on the incidence and epidemiological profile of meningitis in Iran from 2008 to 2014, before pneumococcal conjugate vaccine (PCV) and pentavalent vaccine (DTPw-Hep B-Hib (PRP-T) vaccine (pentavac) (adsorbed)) introduction. 31640619 2019
CUI: C0026837
Disease: Muscle Rigidity
Muscle Rigidity
0.010 Biomarker phenotype BEFREE Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) is a rare hypomyelinating leukodystrophy characterized by infantile or childhood onset of motor developmental delay, progressive rigidity and spasticity, with hypomyelination and progressive atrophy of the basal ganglia and cerebellum due to a genetic mutation of the TUBB4A gene. 30476126 2019
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.010 Biomarker phenotype BEFREE Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) is a rare hypomyelinating leukodystrophy characterized by infantile or childhood onset of motor developmental delay, progressive rigidity and spasticity, with hypomyelination and progressive atrophy of the basal ganglia and cerebellum due to a genetic mutation of the TUBB4A gene. 30476126 2019
CUI: C0028841
Disease: Ocular Hypotension
Ocular Hypotension
0.010 Biomarker disease BEFREE Intracameral platelet-rich plasma (E-PRP) injection was an effective, rapidly effective, and safe procedure for treatment of severe chronic ocular hypotony following glaucoma filtrating surgery. 30295074 2019
CUI: C0032027
Disease: Pityriasis Rubra Pilaris
Pityriasis Rubra Pilaris
0.010 Biomarker disease BEFREE The choroidal parameters were also compared between PRP untreated and PRP-treated DR eyes. 31419954 2019
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.010 Biomarker disease BEFREE To assess the additive effect of PRP in the therapy of vitiligo on the results of the excimer laser. 31541597 2019
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.010 AlteredExpression disease BEFREE The goal of this conducted study was to evaluate the results of published reports which considered ABC transporters' gene expression in pediatric patients with acute leukemia. 30860475 2019
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias
0.010 Biomarker group BEFREE Deficiencies of these ABC proteins can cause dyslipidemia that is associated with health conditions such as atherosclerosis, diabetes, fatty liver disease, and neurodegeneration. 30058354 2019
CUI: C0263374
Disease: Lichen striatus
Lichen striatus
0.010 Biomarker disease BEFREE Intramatricial PRP is a safe and effective therapeutic modality in nail lichen striatus and idiopathic trachyonychia refractory to other treatment options. 30659726 2019
CUI: C0263725
Disease: Hemophilic arthropathy
Hemophilic arthropathy
0.010 Biomarker disease BEFREE The efficacy of PRP and MSCs in haemophilic arthropathy is pending confirmation, which is why they are not currently recommended. 31639263 2019
CUI: C0268009
Disease: Hyperosmolality
Hyperosmolality
0.010 AlteredExpression disease BEFREE We hypothesize that hyperosmolality affects the expression of many SLCs as well as ABC transporters. 30389539 2019
CUI: C0281899
Disease: Prolapsed lumbar disc
Prolapsed lumbar disc
0.010 Biomarker disease BEFREE Condoliase (chondroitin sulfate ABC endolyase), a glycosaminoglycan-degrading enzyme, was approved by the drug regulatory authority in Japan as a newer intradiscal therapy for LDH after clinical studies conducted in Japan demonstrated efficacy and safety for patients with LDH. 30740609 2019