Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027765
Disease: nervous system disorder
nervous system disorder
0.030 GeneticVariation group BEFREE The HIV envelope glycoprotein (gp120) is neurotoxic and has been linked to alterations in mitochondrial function and increased inflammatory gene expression, which are common neuropathological findings in HIV+ cases on ART with neurological disorders. 31748578 2019
CUI: C0027765
Disease: nervous system disorder
nervous system disorder
0.030 Biomarker group BEFREE Here, we characterize a unique macrophage-tropic SIV envelope glycoprotein (Env) variant from two weeks post-infection in blood of an SIVmac251-infected macaque that is closely related to sequences in brain from animals with neurological disease. 24928039 2014
CUI: C0027765
Disease: nervous system disorder
nervous system disorder
0.030 GeneticVariation group BEFREE We did, however, find evidence of extensive mutation and possibly deletions in the env gene in HTLV-I-associated neurological disease. 8778566 1995