|
Hemorrhagic Fever, Ebola
|
0.080 |
Biomarker
|
disease |
BEFREE |
The ZINC58935541 molecule also showed a strong binding affinity towards the receptor cavity of Ebola virus envelope glycoprotein when simulated for 1.2 ns.
|
30786763 |
2019 |
|
Hemorrhagic Fever, Ebola
|
0.080 |
Biomarker
|
disease |
BEFREE |
The first two coding-complete genomes provided actionable information in real-time for the deployment of the rVSVΔG-ZEBOV-GP Ebola virus envelope glycoprotein vaccine, available therapeutics, and sequence-based diagnostic assays.
|
31000464 |
2019 |
|
Hemorrhagic Fever, Ebola
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
Effect of Gamma Irradiation on the Antibody Response Measured in Human Serum from Subjects Vaccinated with Recombinant Vesicular Stomatitis Virus-Zaire Ebola Virus Envelope Glycoprotein Vaccine.
|
31162004 |
2019 |
|
Hemorrhagic Fever, Ebola
|
0.080 |
Biomarker
|
disease |
BEFREE |
However, the 2013-2016 epidemic in western Africa, caused by Ebola virus (EBOV), illustrated the potential of filovirus outbreaks to escalate to a much larger scale (over 28,000 suspected cases). mAbs against the envelope glycoprotein represent a promising therapeutic platform for managing filovirus infections.
|
29500195 |
2018 |
|
Hemorrhagic Fever, Ebola
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
The vaccine consists of live-attenuated recombinant vesicular stomatitis virus (VSV) and adenovirus serotype-5 (Ad5) expressing Ebola envelope glycoprotein.
|
28152326 |
2017 |
|
Hemorrhagic Fever, Ebola
|
0.080 |
Biomarker
|
disease |
BEFREE |
We found that the Ebola virus matrix protein, VP40, and envelope glycoprotein, GP, each cooperate with BST2 to induce NF-κB activity, with maximal activity when all three proteins are expressed.
|
28878074 |
2017 |
|
Hemorrhagic Fever, Ebola
|
0.080 |
Biomarker
|
disease |
BEFREE |
We tested the activity of suramin during CHIKV or Ebola virus infection, using CHIKV and Ebola envelope glycoprotein pseudotyped lentiviral vectors and wild-type CHIKV and Ebola virus.
|
27581733 |
2016 |
|
Hemorrhagic Fever, Ebola
|
0.080 |
Biomarker
|
disease |
BEFREE |
In this study, the modification of HIV vector tropism by pseudotyping with the envelope glycoprotein from vesicular stomatitis virus (VSV), the Zaire Ebola (EboZ) virus, murine leukemia virus (MuLV), lymphocytic choriomeningitis virus (LCMV), Rabies or the rabies-related Mokola virus encoding LacZ as a reporter gene was evaluated qualitatively and quantitatively in human skin xenografts.
|
17268532 |
2007 |