ACTR2, actin related protein 2, 10097

N. diseases: 45; N. variants: 1
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease BEFREE Silencing DLL1 in the Arp2/3 inhibited CD133+ cells did not further abrogate the stem cell phenotype, suggesting DLL1 function requires Arp2/3 complex in glioma initiating cells (GICs). 28380416 2017
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease BEFREE Cofilin‑1 (CFL‑1), which is regulated by the Rac1‑WAVE2‑Arp2/3 signaling pathway, may promote radioresistance in glioma. 27052944 2016
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease BEFREE Inhibition of the Arp2/3 complex significantly affected the ability of glioma cells to migrate and invade. 23969835 2013