Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.320 GeneticVariation disease BEFREE We found 12 SNPs tagging ten loci, including HLA-DRA, IL10, IL23R, JAK2, S100Z, ARPC2, and ECM1, to be associated with UC. 19861958 2010
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.320 Biomarker disease CTD_human Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. 18836448 2008
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.320 GeneticVariation disease BEFREE Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. 18836448 2008
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.320 Biomarker disease LHGDN Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. 18836448 2008
CUI: C0037116
Disease: Silicosis
Silicosis
0.200 Biomarker disease RGD Identification of differentially expressed genes in rat silicosis model by suppression subtractive hybridization analysis. 18685790 2008
Red cell distribution width determination
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
RDW - Red blood cell distribution width result
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0032181
Disease: Platelet Count measurement
Platelet Count measurement
0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Platelet mean volume determination (procedure)
0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
Platelet Component Distribution Width Measurement
0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure
0.100 GeneticVariation phenotype GWASCAT Trans-ethnic meta-analysis of white blood cell phenotypes. 25096241 2014
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE ARPC2 also played an oncogenic role and mediated the promoting role of RBM3 in the proliferation and metastasis of human breast cancer cells. 30720048 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE In addition, ARPC2 was highly associated with the tumor stage, nodal metastasis, and overall survival of patients with BrCa. 31002363 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex. 31571309 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE Therefore, ARPC2 is a potential target for anti-metastatic therapy, and Benp has the clinical potential to block metastasis. 30710516 2019
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.020 Biomarker disease BEFREE In addition, ARPC2 was highly associated with the tumor stage, nodal metastasis, and overall survival of patients with BrCa. 31002363 2019
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.020 Biomarker disease BEFREE RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression. 30720048 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.020 Biomarker group BEFREE Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex. 31571309 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 Biomarker group BEFREE In addition, ARPC2 was highly associated with the tumor stage, nodal metastasis, and overall survival of patients with BrCa. 31002363 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.020 Biomarker disease BEFREE In addition, ARPC2 was highly associated with the tumor stage, nodal metastasis, and overall survival of patients with BrCa. 31002363 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.020 Biomarker disease BEFREE RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression. 30720048 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 AlteredExpression phenotype BEFREE Given that ARPC2 is critical to this progression, the present study focused on ARPC2 activity in breast cancer (BrCa) cell invasion and migration. 31002363 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.020 Biomarker group BEFREE Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex. 31571309 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.020 Biomarker group BEFREE In this study, we found that ARPC2 promoted cell proliferation and invasion in the human cancer cell line MKN-28 using a cell total number assay, MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide) assay, cell colony formation assay, migration assay, invasion assay, and wound healing assay. 28694563 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.020 Biomarker group BEFREE In the association analysis of 110 gastric cancer tissues, ARPC2 showed significant associations with large tumor size, lymph node invasion, and high tumor stage. 28694563 2017