CDKN1A, cyclin dependent kinase inhibitor 1A, 1026

N. diseases: 490; N. variants: 17
Disease: Papilloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030354
Disease: Papilloma
Papilloma 		0.320 GeneticVariation disease BEFREE This occurs through the induction of p21 (CDKN1A) and the recruitment of the repressive DREAM complex to the A3B gene promoter, such that loss of p53 through mutation, or human papilloma virus-mediated inhibition, prevents recruitment of the complex, thereby causing elevated A3B expression and cytosine deaminase activity in cancer cells. 28977491 2017
CUI: C0030354
Disease: Papilloma
Papilloma 		0.320 Biomarker disease LHGDN Expression of the the cyclin-kinase inhibitors p21(WAF1) and p27(Kip1) and the p53 tumor suppressor genes in adult-onset laryngeal papillomas. 12434183 2002
CUI: C0030354
Disease: Papilloma
Papilloma 		0.320 Biomarker disease CTD_human Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors. 12151359 2002