CDKN1B, cyclin dependent kinase inhibitor 1B, 1027

N. diseases: 454; N. variants: 20
Disease: Lung Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker group CTD_human Epigenetic silencing of cell cycle regulatory genes during 3-methylcholanthrene and diethylnitrosamine-induced multistep rat lung cancer. 20512841 2010
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker group CTD_human A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression. 16391232 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 AlteredExpression group LHGDN Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer. 16966613 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker group CTD_human Loss of the cell cycle inhibitors p21(Cip1) and p27(Kip1) enhances tumorigenesis in knockout mouse models. 12466968 2002
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 AlteredExpression group BEFREE Our immunohistochemical examination of 166 lung tumor specimens also revealed a striking difference in p27KIP1 expression between SCLCs and NSCLCs. 9500468 1998