Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.060 AlteredExpression group BEFREE It can also be proposed that ALR levels are not affected by diabetes only, suggesting that their alterations in T2DM may be due to obesity as we observed more ALR changes in obese cases when compared to T2DM cases, and so there might be an important link between adiposity and insulin resistance. 27705028 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.060 Biomarker group BEFREE Aldose reductase (ALR), the first and rate-limiting enzyme involved in polyol pathway plays a central role in diabetes and its related complications, including diabetic retinopathy (DR). 27835059 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.060 Biomarker group BEFREE Biochemical Gas Sensors (Biosniffers) Using Forward and Reverse Reactions of Secondary Alcohol Dehydrogenase for Breath Isopropanol and Acetone as Potential Volatile Biomarkers of Diabetes Mellitus. 29120608 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.060 GeneticVariation group BEFREE However, subgroup analysis showed a genetic association between ALR C(-106)T polymorphism and the risk of DR of type 1 DM but not DR of type 2 DM. 25722213 2015
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.060 Biomarker group BEFREE Independent genetic mapping studies have identified ALR-derived diabetes protective loci. 19120287 2008
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.060 GeneticVariation group BEFREE To ascertain why alcohol is prone to manifest unpleasant effects in diabetes associated with mitochondrial tRNA(Leu(UUR) mutation at position 3243 (DM-Mt3243), we investigated the genotype of aldehyde dehydrogenase (ALDH) 2 and alcohol dehydrogenase 2 (ADH2) in DM-Mt3243. 8941476 1996