DLC1, DLC1 Rho GTPase activating protein, 10395

N. diseases: 144; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.310 Therapeutic disease CTD_human Overexpression of AFT-3 also enhanced caspase-3 activity in both HOSE and OVCA cells, whereas ectopic expression of caveolin-1 and DLC-1 only activated this enzyme in OCa cells. 15674352 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.310 Biomarker disease BEFREE The rarity of exonic missense mutations, and the absence of protein-truncating mutations, indicates that DLC1 is not the target of 8p LOH in colorectal or ovarian tumours. 10649492 2000