Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Two upregulated (EpCAM, FADD) and two downregulated (NDRG1, αB-crystallin) proteins were associated with the progression of breast cancer.
|
31443698 |
2019 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In breast cancer, elevated NDRG1 expression has been linked to clinical outcomes, but its functional role in breast cancer physiology has remained unclear.
|
29898756 |
2018 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The hypoxia-responsive lncRNA <i>NDRG-OT1</i> promotes NDRG1 degradation via ubiquitin-mediated proteolysis in breast cancer cells.
|
29535820 |
2018 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways related to cancer progression and gene regulation were found to be enriched in those overlaps.In the PPI network, NDRG1, JUP and etc. were found to directly interact with large number of genes, which might indicate their important roles in the progression of breast cancer.
|
27654269 |
2017 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We have aimed to demonstrate the impact of TGF-β1 and fluvastatin on human breast cancer (MCF-7) and human hepatocellular carcinoma (Hep3B) cell cultures via Real-Time Cell Analyzer (RTCA) and to test the expression levels of some genes (NDRG1, SGK1, TWIST1, AMPKA2) and to compare their gene expression levels according to RTCA results.
|
26419593 |
2016 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The analysis revealed that the lipid transport related genes LAPTM4B and NDRG1 are coamplified in breast cancer patients, and identified genes potentially cooperating with LAPTM4B in breast cancer progression.
|
27711123 |
2016 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Aryl Hydrocarbon Receptor Activates NDRG1 Transcription under Hypoxia in Breast Cancer Cells.
|
26852918 |
2016 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Moreover, forced overexpression of WISP1 blocked the expression of NDRG1, a breast cancer tumor suppressor gene.
|
25732125 |
2015 |
Breast Carcinoma
|
0.400 |
PosttranslationalModification
|
disease |
BEFREE |
DNA methylation in the NDRG1 promoter was detected in 31.1% of primary breast cancer samples.
|
23899187 |
2013 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
PTEN expression has been shown to be correlated with NDRG1 in both prostate and breast cancer.
|
18653908 |
2008 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Treatment with estradiol (E(2)) significantly decreased the expression of Cap43 in ER-alpha-positive breast cancer cell lines.
|
18224398 |
2008 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Immunohistochemistry was used to evaluate the expression of the Cap43 protein in breast cancer patients (n = 96), and the relationship between Cap43 expression and clinicopathologic findings was examined.
|
16707596 |
2006 |
Breast Carcinoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Consistent with these results, our immunohistochemical analysis revealed that PTEN expression correlates significantly with Drg-1 in both prostate and breast cancer cases.
|
15520163 |
2004 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Together, our results strongly suggest functional involvement of the Drg-1 gene in suppressing the metastatic advancement of human breast cancer.
|
15184886 |
2004 |
Breast Carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers.
|
15341671 |
2004 |