Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.030 Biomarker group BEFREE Thus, we conclude that the <i>STAT3</i> pathway plays a role in the development and progression of HGSC from its earliest premalignant states.<b>Significance:</b> Concomitant gain of pSTAT3 Tyr705 and loss of PIAS3 appear critical for initiation and development of high-grade serous carcinoma.<i>Cancer Res; 78(7); 1739-50.©2018 AACR</i>. 29339537 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.030 AlteredExpression group BEFREE These results suggest that PIAS3 protein expression impacts survival in patients with mesothelioma and that PIAS3 activation could become a therapeutic strategy.Clin Cancer Res; 20(19); 5124-32.©2014 AACR. 25124686 2014
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.030 AlteredExpression group BEFREE Differential PIAS3 expression and the specific patterns may be useful as a molecular marker of human cancer. 15138572 2004