CPQ, carboxypeptidase Q, 10404

N. diseases: 87; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 PosttranslationalModification disease BEFREE Among these genes, the hypermethylation of the plasma glutamate carboxypeptidase (PGCP) gene appeared specifically in lung cancer tissues. 29196255 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE Historically, bestatin was the first prototypical aminopeptidase inhibitor that entered the clinic 35 years ago and is still used for the treatment of lung cancer. 24385243 2014
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.030 Biomarker disease BEFREE These findings suggest that hlFVII-LDP-AE is efficacious and tolerated in the mouse model of NCI-H292 human lung cancer examined and could have broad clinical applicability for treating cancer patients. 22108624 2012