Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 AlteredExpression phenotype BEFREE The interferon-induced transmembrane protein 3 (IFITM3, also called 1‑8U) gene represents dysregulated expression in various tumors and is involved in tumorigenesis and progression. 30272306 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Chemical induction of colitis in IFITM3-deficient mice results in significantly increased clinical signs of inflammation and induction of invasive tumorigenesis. 29356071 2018
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Interferon induced transmembrane protein 3 (IFITM3) plays an important role in the tumorigenesis and progression of multiple cancers. 28544512 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Recent research has shown that IFITM3 plays an important role in the tumorigenesis of many malignancies. 28857475 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 AlteredExpression phenotype BEFREE Depletion of IFITM3in U251 cells dramatically inhibited cell proliferation and colony formation, which demonstrated that reduced IFITM3 protein levels could cause inhibition of tumorigenesis. 24370119 2013
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Gene-expression profiling in Chinese patients with colon cancer by coupling experimental and bioinformatic genomewide gene-expression analyses: identification and validation of IFITM3 as a biomarker of early colon carcinogenesis. 18470904 2008