YAP1, Yes associated protein 1, 10413

N. diseases: 374; N. variants: 15
Disease: Malignant neoplasm of ovary ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.360 Biomarker disease BEFREE Yes-associated protein 1 (YAP1) is a key transcriptional regulator in the Hippo signaling pathway that plays a critical role in the development and progression of several types of malignancies, including ovarian cancer. 28339095 2017
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.360 Biomarker disease BEFREE PKCι regulates nuclear YAP1 localization and ovarian cancer tumorigenesis. 27321186 2017
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.360 Biomarker disease BEFREE The PRKCI-YAP1 regulation of the tumor immunity provides a therapeutic strategy for highly lethal ovarian cancer. 28698296 2017
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.360 Biomarker disease BEFREE GEP oncogene promotes cell proliferation through YAP activation in ovarian cancer. 26804165 2016
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.360 AlteredExpression disease BEFREE We identified a 612-gene expression signature reflecting YAP1 activation in ovarian cancer. 24511017 2014
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.360 Biomarker disease BEFREE Taken together, our data first indicate that YAP/TEAD co-activator regulated ovarian cancer initiated cell pluripotency and chemo-resistance. 25369529 2014
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.360 Biomarker disease CTD_human Hippo pathway effector Yap is an ovarian cancer oncogene. 20947521 2010