CDX1, caudal type homeobox 1, 1044

N. diseases: 54; N. variants: 1
Disease: Colonic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.030 PosttranslationalModification group BEFREE Colon tumor-specific DNA methylation at Cdx1 is reduced in the DNA-hypomethylated tumors accompanied by Cdx1 derepression and an increased expression of intestinal differentiation-related genes. 25939752 2015
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.030 AlteredExpression group LHGDN Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors. 18187048 2008
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.030 AlteredExpression group LHGDN Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity. 15215241 2004