CDX2, caudal type homeobox 2, 1045

N. diseases: 278; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 Biomarker disease BEFREE To gain better insight into the involvement of Cdx2 in the biological characteristics of gastric cancer, we investigated the effect of Cdx2 overexpression on the progression of gastric carcinoma cells. 20043087 2010
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 Biomarker disease BEFREE However, the trends were similar between PTEN and Cdx2 in GC tissues and cell lines. 23546539 2013
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 AlteredExpression disease BEFREE Aberrant Cdx2 expression has been shown in precancerous lesions as well as GC. 22104201 2011
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 AlteredExpression disease BEFREE our results confirm that CDX2 expression in gastric carcinoma is associated with improved prognosis, although further studies are needed to draw definitive conclusions. 31140285 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 Biomarker disease BEFREE CDX2 is a tumor-suppressor homeobox gene involved in colon carcinogenesis, but its role in gastric cancer is unknown. 10942535 2000
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.100 Biomarker disease BEFREE CDX2 had an inhibitory effect on the MGC-803 human gastric cancer cell line and promoted tumor cell apoptosis in vivo. 25738600 2015