Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease BEFREE Interestingly, LRRK2 interacted with TOM40 under both DMSO and CCCP conditions, and when the PD causing mutation, G2019S was introduced, the association was not altered. 30597143 2019
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease BEFREE The role of <i>TOMM40-APOE</i> 19q13.3 region variants is well documented in Alzheimer's disease (AD) but remains contentious in dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). 31788537 2019
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease BEFREE To investigate the role of the Translocase of the Outer Mitochondrial Membrane 40 homolog (TOMM40) variants in PD without dementia (PDND), PD with dementia (PDD) and in Dementia with Lewy bodies (DLB). 26756745 2016
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 Biomarker disease BEFREE TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease. 23626796 2013
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.050 GeneticVariation disease BEFREE TOMM40 and APOE common genetic variants are not Parkinson's disease risk factors. 23522842 2013