|
Malignant neoplasm of breast
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
FST expression was examined using reverse transcription polymerase chain reaction (RT-PCR), real-time quantitative polymerase chain reaction (qPCR) and immunohistochemistry in a cohort of breast cancer samples.
|
28647698 |
2018 |
|
Malignant neoplasm of breast
|
0.370 |
Biomarker
|
disease |
BEFREE |
In summary, MCF7 cells show high chemosensitivity to Follistatin and especially GDF8 and both proteins might serve as targets to improve systemic treatment in breast cancer.
|
29156385 |
2018 |
|
Malignant neoplasm of breast
|
0.370 |
Biomarker
|
disease |
BEFREE |
Despite experimental evidence that follistatin can modulate the breast cancer cell cycle, the clinical significance of follistatin expression in these tumors is unknown.
|
27389553 |
2018 |
|
Breast Carcinoma
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
FST expression was examined using reverse transcription polymerase chain reaction (RT-PCR), real-time quantitative polymerase chain reaction (qPCR) and immunohistochemistry in a cohort of breast cancer samples.
|
28647698 |
2018 |
|
Breast Carcinoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
In summary, MCF7 cells show high chemosensitivity to Follistatin and especially GDF8 and both proteins might serve as targets to improve systemic treatment in breast cancer.
|
29156385 |
2018 |
|
Breast Carcinoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
Despite experimental evidence that follistatin can modulate the breast cancer cell cycle, the clinical significance of follistatin expression in these tumors is unknown.
|
27389553 |
2018 |
|
Malignant neoplasm of breast
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Examination of multiple breast cancer datasets revealed that FST expression is reduced in breast cancers compared with normal tissue and that low FST expression predicts increased metastasis and reduced overall survival.
|
28583174 |
2017 |
|
Breast Carcinoma
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Examination of multiple breast cancer datasets revealed that FST expression is reduced in breast cancers compared with normal tissue and that low FST expression predicts increased metastasis and reduced overall survival.
|
28583174 |
2017 |
|
Malignant neoplasm of breast
|
0.370 |
Biomarker
|
disease |
BEFREE |
Therefore, we concluded that FST and KLK6 may have significance in breast cancer detection.
|
27168011 |
2016 |
|
Breast Carcinoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
Therefore, we concluded that FST and KLK6 may have significance in breast cancer detection.
|
27168011 |
2016 |
|
Malignant neoplasm of breast
|
0.370 |
Biomarker
|
disease |
BEFREE |
Overexpressed ERRβ induced FST-mediated apoptosis in breast cancer cells, and E-cadherin expression was also enhanced through upregulation of FST.
|
24667650 |
2014 |
|
Breast Carcinoma
|
0.370 |
Biomarker
|
disease |
BEFREE |
Overexpressed ERRβ induced FST-mediated apoptosis in breast cancer cells, and E-cadherin expression was also enhanced through upregulation of FST.
|
24667650 |
2014 |
|
Malignant neoplasm of breast
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
As activin displays an anti-proliferative effect in human mammary cells, the present findings indicate that an increased FST and FLRG expression in breast proliferative diseases might counteract the anti-proliferative effects of activin in human breast cancer.
|
19740438 |
2009 |
|
Breast Carcinoma
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
As activin displays an anti-proliferative effect in human mammary cells, the present findings indicate that an increased FST and FLRG expression in breast proliferative diseases might counteract the anti-proliferative effects of activin in human breast cancer.
|
19740438 |
2009 |
|
Malignant neoplasm of breast
|
0.370 |
Biomarker
|
disease |
CTD_human |
ERE-independent ERalpha target genes differentially expressed in human breast tumors.
|
16298037 |
2005 |
|
Breast Carcinoma
|
0.370 |
Biomarker
|
disease |
CTD_human |
ERE-independent ERalpha target genes differentially expressed in human breast tumors.
|
16298037 |
2005 |
|
Liver carcinoma
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
FST is differentially expressed in human tissues and aberrant expression has been observed in a variety of solid tumours, including gonadal, gastric and lung cancer, hepatocellular carcinoma, basal cell carcinoma and melanoma.
|
27807065 |
2017 |
|
Liver carcinoma
|
0.330 |
Biomarker
|
disease |
CTD_human |
Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression.
|
19363144 |
2009 |
|
Liver carcinoma
|
0.330 |
Biomarker
|
disease |
BEFREE |
We conducted a cross sectional study assessing the value of these serum proteins, as well a novel candidate biomarker -follistatin - in patients with HCC arising on a background of ALD or NAFLD.
|
18638391 |
2008 |
|
Liver carcinoma
|
0.330 |
Biomarker
|
disease |
CTD_human |
Follistatin expression was also observed in cell lines derived from human hepatocellular carcinomas.
|
12203361 |
2002 |
|
Liver carcinoma
|
0.330 |
AlteredExpression
|
disease |
BEFREE |
Follistatin expression was also observed in cell lines derived from human hepatocellular carcinomas.
|
12203361 |
2002 |
|
Mammary Neoplasms
|
0.320 |
Biomarker
|
group |
BEFREE |
Follistatin Expression in Human Invasive Breast Tumors: Pathologic and Clinical Associations.
|
27389553 |
2018 |
|
Miscarriage
|
0.320 |
AlteredExpression
|
disease |
BEFREE |
In humans, FST is up-regulated in the decidua during early pregnancy, and women with recurrent miscarriage have lower endometrial expression of FST during the luteal phase.
|
28559342 |
2017 |
|
Mammary Neoplasms
|
0.320 |
Biomarker
|
group |
BEFREE |
In order to establish if these activin binding proteins are involved in breast tumor progression, the present study evaluated follistatin and FLRG pattern of mRNA and protein expression in normal human breast tissue and in different breast proliferative diseases.
|
19740438 |
2009 |
|
Miscarriage
|
0.320 |
Biomarker
|
disease |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |