FST, follistatin, 10468

N. diseases: 182; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 GeneticVariation group BEFREE Among the identified variants, two are near genes known to regulate hormones and diseases of the ovary (AKR1C3 and FST), and two are linked to cancer (AKR1C3 and MAGEC1). 31469419 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 Biomarker group BEFREE In the present study, we have reviewed the actions of activin and its biological inhibitors, inhibin, and follistatin, in mammary gland morphogenesis and cancer. 30874767 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 Biomarker group BEFREE Activin A, a member of the TGFβ family, and its antagonist Follistatin are involved in several human malignancies and angiogenesis. 31757999 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 Biomarker group BEFREE These studies provide the data to support further investigation of the use of follistatin to reduce radiation-induced fibrosis in patients undergoing radiotherapy for cancer. 28301516 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 AlteredExpression group BEFREE In the past decades, altered Follistatin‑like 1 (FSTL1) expression has been documented in a variety of cancers, while its functional roles are poorly understood. 29048681 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 Biomarker group BEFREE Altogether, we identified a novel nucleolar function of FST, which is of importance in the modulation of cancer cell survival in response to glucose deprivation. 20843798 2010
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 Biomarker group BEFREE However, the role of FST in cancer metastasis is still unknown. 18245525 2008
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 AlteredExpression group BEFREE Activin and follistatin (FS) messenger RNA and protein are expressed and localized to human prostate tissue from men with high grade cancer and to human prostate tumor cell lines LNCaP, DU145, and PC3. 10537161 1999
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.090 Biomarker group BEFREE In the progression to malignancy, the colocalization of follistatin and activins to the tumor cells in vivo implies that resistance to the growth inhibitory effects of activin may be conferred by follistatins. 9360551 1997