FST, follistatin, 10468

N. diseases: 182; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.060 AlteredExpression phenotype BEFREE These data suggest that serum FST levels not only can be used in auxiliary diagnosis for lung cancer but also might be associated with the disease progression and metastasis of lung cancers. 30377409 2018
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.060 Biomarker phenotype BEFREE Our results suggest a role for FST as a suppressor of invasion and metastasis in breast cancer. 28647698 2018
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.060 AlteredExpression phenotype BEFREE Examination of multiple breast cancer datasets revealed that FST expression is reduced in breast cancers compared with normal tissue and that low FST expression predicts increased metastasis and reduced overall survival. 28583174 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.060 Biomarker phenotype BEFREE FST plays a role in tumourigenesis, metastasis and angiogenesis of solid tumours through its interaction with activin and BMPs, thus resulting in pathophysiological function. 27807065 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.060 AlteredExpression phenotype BEFREE Importantly, matrix metalloprotease 7, which is a classical mediator of metastasis and E-cadherin cleavage, was also restricted as a result of ERRβ-mediated FST overexpression. 24667650 2014
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.060 Biomarker phenotype BEFREE The purpose of this study is to determine the role of FST in multiple-organ metastasis using this model. 18245525 2008
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.060 Biomarker phenotype LHGDN Immunohistochemical analyses of the liver metastases revealed that the number of proliferating tumor cells and the tumor-associated microvessel density were significantly less in the lesions produced by FST transfectants. 18245525 2008