|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
DCS re-sensitised MRSA to β-lactams in vitro and significantly enhanced MRSA eradication by oxacillin in a mouse bacteraemia model.
|
31628459 |
2020 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
We collected 59 MRSA isolates from adult patients with bacteremia.
|
31721291 |
2020 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Univariate analysis revealed that infection was more frequent in patients with MRSA-carriage (p < 0.001), in case of previous catheter-related infection (p < 0.05) and of bacteremia or bacteriuria in the period of 3 months before catheter implantation (p < 0.001).
|
31151433 |
2019 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
We found a high incidence of E faecium and a low incidence of MRSA and Pseudomonas bacteremias following ASCT in our patient population.
|
30689291 |
2019 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Thirty-day readmission rate was 22% (SE, 0.3) overall with no difference between MRSA and MSSA, but MRSA bacteremia had more readmission for bacteremia recurrence (hazard ratio, 1.17 [95% confidence interval {CI}, 1.02-1.34]), higher in-hospital mortality (odds ratio, 1.15 [95% CI, 1.07-1.23]), and longer hospitalization (incidence rate ratio, 1.09 [95% CI, 1.06-1.11]).
|
30753447 |
2019 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In an era of community acquired MRSA, colonization status appears to be the only independent and reliable predictor of MRSA infection in cases of S. aureus bacteremia.
|
29890954 |
2018 |
|
Bacteremia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Risk ratios for recurrent bacteremia after a single- and co-nonsusceptible first episode, respectively, vs susceptible first episode, were 1.7 (95% confidence interval [CI], 1.5-2.0) and 5.2 (95% CI, 2.1-12.4) for Enterobacteriaceae, 1.3 (95% CI, 0.5-3.1) and 5.0 (95% CI, 2.9-8.5) for Pseudomonas species, 1.4 (95% CI, 1.2-1.7) and 1.6 (95% CI, 0.6-4.2) for Enterococcus species, and 1.6 (95% CI, 1.1-2.4) for MRSA vs MSSA.
|
29228127 |
2018 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Of 500 hospital-onset Staphylococcus aureus bacteremia events (58% methicillin-susceptible S. aureus [MSSA]; 42% methicillin-resistant S. aureus [MRSA]), we found no significant differences in S. aureus bacteremia rates between medium-sized and large hospitals.
|
29429428 |
2018 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In conclusion, the comorbidities, disease severity and antibiotic regimen remained the most relevant factors predicting treatment failure and 30-day mortality in patients with MRSA-RVS bacteremia. hIVSA phenotype was the only bacterial factor potentially associated with unfavorable outcome in this cohort.
|
29777150 |
2018 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Compared to MRSA BSI patients, <i>mecA</i>-MSSA BSI patients more often experienced clinical failure (58.8% and 11.8%, <i>P</i> = 0.010), driven largely by persistent bacteremia (35.3% and 11.8%).
|
29038267 |
2018 |
|
Bacteremia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Age-related trends in critical illness (a Pitt bacteremia score of ≥4) at bacteremia onset, antibiotic-resistant pathogens (extended-spectrum β-lactamase [ESBL]-producing <i>Escherichia coli</i>, <i>Klebsiella</i> species, and <i>Proteus mirabilis</i> [EKP]; methicillin-resistant <i>Staphylococcus aureus</i> [MRSA]; and levofloxacin nonsusceptible EKP), inappropriate empirical antibiotic therapy (EAT), and 4-week mortality rate were observed.
|
28923864 |
2017 |
|
Bacteremia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
<b>Conclusions:</b> Although MRSA were uncommon, we found high genetic diversity of methicillin susceptible <i>S. aureus</i> causing bacteremia in Mozambican children, associated with high resistance to the most available antibiotics in this community.
|
28522992 |
2017 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
The overall prevalence of MRSA among those with SAB was 30.9% (231/747; 95% confidence interval [CI] 27.6%- 34.3%).
|
29145465 |
2017 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Bacteremia (led by MRSA and Acinetobacter baumannii) was documented in 14.6 %, being associated with extra ICU stay and mortality.
|
27287765 |
2017 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study demonstrates that S. aureus bacteraemia is common in South African academic centres and characterised by HA-MRSA SCCmec types III and IV.
|
28849285 |
2017 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Meanwhile, case reports, case series and few studies have demonstrated the capability of LA-MRSA to cause all types of infections attributed to S. aureus in general including fatal courses.Human infections observed comprise e.g. bacteremia, pneumonia, osteomyelitis, endocarditis and many manifestations of skin and soft tissue infections.
|
26644311 |
2017 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Among a total of 818 MRSA isolates, we identified ten isolates of PVL-positive ST8-MRSA (USA300) (3 from Hospital D, 4 from Hospital G, and 3 from Hospital A), all of which involved exclusively healthcare-associated (5 isolates) and hospital-acquired bacteraemia (5 isolates).
|
27209287 |
2016 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Deletion of edinB in a European lineage community-acquired methicillin resistant S. aureus (CA-MRSA) strain (ST80-MRSA-IV) dramatically decreased the frequency and magnitude of bacteremia in mice suffering from pneumonia.
|
26501320 |
2015 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
We aimed to evaluate a PCR-based rapid diagnosis of methicillin resistance (GeneXpert MRSA) after early detection of S. aureus bacteraemia using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS).
|
23991748 |
2014 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, molecular methods able to detect and differentiate S. aureus and MRSA (SA/MRSA) directly from blood cultures are becoming a useful tool for rapid detection of bacteremia caused by MSSA and MRSA.
|
24085689 |
2014 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
CA-MRSA isolates accounted for 73% of all S. aureus recovered from invasive (mainly bone and joint) infections, pneumonia and bacteraemia.
|
23324815 |
2013 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Recently (2009-2010), the distribution of predominant MRSA clones decreased, whilst the prevalence of non-predominant MSSA clones increased, especially for the isolates causing bacteraemia.
|
23118474 |
2013 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Among 131 episodes of S. aureus bacteremia, 85 (66%) were MRSA of which 47 (54%) were CA-MRSA.
|
22040268 |
2011 |
|
Bacteremia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In summary, CA-MRSA bacteremia was not common in our hospital during the period.
|
20735176 |
2010 |
|
Bacteremia
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Twenty-six (10.4%) CA-MRSA nosocomial infection-causing strains (eg, USA300) were detected in 250 MRSA infection isolates in mainly primary bacteremia and surgical site infections.
|
20042253 |
2010 |