SLC9A6, solute carrier family 9 member A6, 10479

N. diseases: 210; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE The main goal of this study was to evaluate PK/pharmacodynamic (PKPD) target attainment when using a 600 mg intravenous q12h linezolid dose against MRSA in obese patients with pneumonia. 30535122 2019
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE However, little is known about the role of IL-17 in CA-MRSA pneumonia. 30026066 2019
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 GeneticVariation disease BEFREE More patients with qSOFA ≥2 had altered mentation (23% vs 5%, p < 0.0001), were infected with MRSA (42% vs 30%, p = 0.03), had endocarditis or pneumonia (29% vs 15%, p = 0.0028), and bacterial persistence ≥4d (34% vs 20%, p = 0.0039) compared to qSOFA <2 patients. 30760213 2019
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE Thirteen ICUs enrolled 48 patients, with pneumonia attributable to MRSA in six subjects. 30343314 2018
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE The addition of rifampicin significantly improved the efficacy of linezolid in the pneumonia model due to cfr-positive and cfr-negative MRSA strains. 29897466 2018
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE The objective of this study was to evaluate the impact of pharmacist-ordered methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) PCR testing on the duration of empirical MRSA-targeted antibiotic therapy in patients with suspected pneumonia. 28137813 2017
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE Deletion of edinB in a European lineage community-acquired methicillin resistant S. aureus (CA-MRSA) strain (ST80-MRSA-IV) dramatically decreased the frequency and magnitude of bacteremia in mice suffering from pneumonia. 26501320 2015
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE Transcriptional events during the recovery from MRSA lung infection: a mouse pneumonia model. 23936388 2013
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE Capsaicin inhibits the production of α-toxin by CA-MRSA strain USA 300 in vitro and protects mice from CA-MRSA pneumonia in vivo. 22427935 2012
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.100 Biomarker disease BEFREE We conclude that ACME is not necessary for virulence in rodent models of CA-MRSA USA300 pneumonia or skin infection. 19380473 2009