Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Therefore, we recommend routinely performing ascites CEA analysis in colorectal cancer surgery. 31802190 2020
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Preoperative neutrophil-lymphocyte ratio and CEA is associated with poor prognosis in patients with synchronous colorectal cancer liver metastasis. 30941323 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Effects of vitamin D and omega-3 fatty acids co-supplementation on inflammatory biomarkers, tumor marker CEA, and nutritional status in patients with colorectal cancer: a study protocol for a double blind randomized controlled trial. 31815661 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Since carcinoembryonic antigen (CEA; CEACAM5) is abundantly overexpressed in colorectal cancer, it is a potential target for tPDT of colorectal cancer. 31828541 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Older age, male sex, African-American race, elevated CEA and not undergoing curative surgery were independent risk factors of cardiovascular mortality in patients with colorectal cancer. 30604158 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Overall, CEA remains a reliable predictor of recurrence and survival after curative surgery in patients with colorectal cancer. 30822523 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE All patients with colorectal cancer underwent a surveillance colonoscopy for recurrence; 97% had a carcinoembryonic antigen test. 30615587 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Impact of CEA-targeting Nanoparticles for Drug Delivery in Colorectal Cancer. 30670480 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE The higher serum CEA level than that of healthy individuals led to its clinical application as a diagnostic biomarker for colorectal cancer. 30905451 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Physiologically Based Modeling of the Pharmacokinetics of "Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibodies in Colorectal Cancer Xenograft Mouse Models. 30321546 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Applicability of postoperative carcinoembryonic antigen levels in determining post-liver-resection adjuvant chemotherapy regimens for colorectal cancer hepatic metastasis. 31689796 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE BACKGROUND Type 2 diabetes mellitus (T2DM) is related to the serum carcinoembryonic antigen (CEA) level, which is used as a marker of colorectal cancer. 31086125 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Carcinoembryonic antigen (CEA) is a commonly used biomarker in colorectal cancer. 31543685 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE This novel oversecretion of LAMB1 was validated in colorectal cancer patient serum samples, and ROC analyses showed that LAMB1 performed better than carcinoembryonic antigen (CEA) as a clinical diagnostic biomarker for colorectal cancer. 30980318 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE The clinical impact of monitoring serum p53 antibodies, carbohydrate antigen19-9, and carcinoembryonic antigen in patients with colorectal cancer has not been fully evaluated. 31820210 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Methylated Septin 9 and Carcinoembryonic Antigen for Serological Diagnosis and Monitoring of Patients with Colorectal Cancer After Surgery. 31316143 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE In vivo, a murine surrogate of HERA-CD40L-stimulated clonal expansion of OT-I-specific murine CD8 T cells and showed single agent antitumor activity in the CD40 syngeneic MC38-CEA mouse model of colorectal cancer, suggesting an involvement of the immune system in controlling tumor growth. 30273198 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE The aim of the study is to determine the value of elevated pre- and postoperative serum carcinoembryonic antigen levels (CEA > 5 µg/L) as an independent prognostic factor for locoregional and distant recurrence in patients who underwent curative surgery for colorectal cancer. 30852955 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Serum tumor markers, including CEA and CA19-9, have become the focus of research on colorectal cancer in recent years. 30854125 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE To test this hypothesis, we analyzed CEA and CA19-9 serum levels in patients with advanced colorectal cancer who received cetuximab in combination with chemotherapy. 30805037 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Carcinoembryonic antigen (CEACAM5, CEA) is a known tumor marker for colorectal cancer that localizes in a polarized manner to the apical surface in normal colon epithelial cells whereas in cancer cells it is present at both the apical and basolateral surfaces of the cells. 29304557 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE To examine overall mortality, colorectal cancer-specific mortality, and colorectal cancer-specific recurrence rates among patients with stage II or III colorectal cancer who were randomized after curative surgery to 2 alternative schedules for follow-up testing with computed tomography and carcinoembryonic antigen. 29800179 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE A microfluidic paper analytical device (μPAD) was created for the sensitive quantification of cancer antigens, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9), from human whole blood and serum, toward diagnosis and prognosis of colorectal cancer. 28922620 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Glycan analysis of colorectal cancer samples reveals stage-dependent changes in CEA glycosylation patterns. 29507546 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Evaluation of Serum CEA, CA19-9, CA72-4, CA125 and Ferritin as Diagnostic Markers and Factors of Clinical Parameters for Colorectal Cancer. 29426902 2018