Tonsillitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
<i>In vitro</i>, repeated TLR9 stimulation induced APRIL expression in tonsillar B cells from control patients with tonsillitis.
|
27920152 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Tumor growth-promoting as well as apoptosis-inducing effects of APRIL have been described.
|
11550092 |
2001 |
Neoplasms
|
0.100 |
PosttranslationalModification
|
group |
BEFREE |
APRIL and BAFF are involved in a variety of tumor and autoimmune diseases, including B-cell malignancies.
|
15070697 |
2004 |
Autoimmune Diseases
|
0.060 |
PosttranslationalModification
|
group |
BEFREE |
APRIL and BAFF are involved in a variety of tumor and autoimmune diseases, including B-cell malignancies.
|
15070697 |
2004 |
Autoimmune Diseases
|
0.060 |
Biomarker
|
group |
BEFREE |
APRIL may serve as a down modulator of serological and/or clinical autoimmunity in patients with SLE.
|
15308519 |
2004 |
Rheumatoid Arthritis
|
0.070 |
Biomarker
|
disease |
BEFREE |
APRIL stimulated RA FLS, but not OA FLS, to produce IL-6, TNFalpha, IL-1beta, and APRIL itself.
|
17968879 |
2007 |
Primary malignant neoplasm
|
0.050 |
AlteredExpression
|
group |
BEFREE |
APRIL is overexpressed in cancer: link with tumor progression.
|
19291294 |
2009 |
Tumor Cell Invasion
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
APRIL knockdown suppresses migration and invasion of human colon carcinoma cells.
|
19573525 |
2009 |
Immune thrombocytopenic purpura
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
APRIL is over expressed in untreated active ITP patients and might be a pathogenic factor of this disorder.
|
19824872 |
2009 |
Adenocarcinoma of large intestine
|
0.010 |
Biomarker
|
disease |
BEFREE |
APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling.
|
20003335 |
2009 |
Membranous Lupus Nephritis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
APRIL was prominently expressed in glomeruli with proliferative, but not membranous, lupus nephritis.
|
20890272 |
2011 |
Malignant Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
APRIL has also been associated with a wide range of solid malignancies, including colorectal cancer (CRC).
|
22705846 |
2012 |
Lupus Nephritis
|
0.020 |
Biomarker
|
disease |
BEFREE |
APRIL could be a potential biomarker for predicting difficult-to-treat cases of lupus nephritis.
|
23171638 |
2012 |
Carcinogenesis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
APRIL induces tumorigenesis and metastasis of colorectal cancer cells via activation of the PI3K/Akt pathway.
|
23383143 |
2013 |
Neoplasm Metastasis
|
0.040 |
Biomarker
|
phenotype |
BEFREE |
APRIL induces tumorigenesis and metastasis of colorectal cancer cells via activation of the PI3K/Akt pathway.
|
23383143 |
2013 |
leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
APRIL-TCL1 double-Tg mice showed a significantly earlier onset of leukemia and disruption of splenic architecture, and survival was significantly reduced.
|
24100449 |
2013 |
Childhood Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
APRIL-TCL1 double-Tg mice showed a significantly earlier onset of leukemia and disruption of splenic architecture, and survival was significantly reduced.
|
24100449 |
2013 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
APRIL can stimulate tumor cell growth and is up-expressed in cancer tissues, especially in CRC (colorectal cancer).
|
24771268 |
2014 |
Malignant Neoplasms
|
0.060 |
AlteredExpression
|
group |
BEFREE |
APRIL can stimulate tumor cell growth and is up-expressed in cancer tissues, especially in CRC (colorectal cancer).
|
24771268 |
2014 |
Primary malignant neoplasm
|
0.050 |
AlteredExpression
|
group |
BEFREE |
APRIL can stimulate tumor cell growth and is up-expressed in cancer tissues, especially in CRC (colorectal cancer).
|
24771268 |
2014 |
Colorectal Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
APRIL can stimulate tumor cell growth and is up-expressed in cancer tissues, especially in CRC (colorectal cancer).
|
24771268 |
2014 |
Malignant neoplasm of colon and/or rectum
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
APRIL can stimulate tumor cell growth and is up-expressed in cancer tissues, especially in CRC (colorectal cancer).
|
24771268 |
2014 |
Malignant neoplasm of stomach
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
APRIL mRNA levels were significantly increased in GC tissues compared with adjacent tissues and high expression levels of APRIL in tumor cells significantly correlated with poor overall survival in patients receiving cisplatin adjuvant treatment.
|
25612651 |
2015 |
Stomach Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
APRIL mRNA levels were significantly increased in GC tissues compared with adjacent tissues and high expression levels of APRIL in tumor cells significantly correlated with poor overall survival in patients receiving cisplatin adjuvant treatment.
|
25612651 |
2015 |
Neoplasm Metastasis
|
0.040 |
Biomarker
|
phenotype |
BEFREE |
APRIL promotes breast tumor growth and metastasis and is associated with aggressive basal breast cancer.
|
25750171 |
2015 |