Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis
0.030 AlteredExpression disease BEFREE Compared with healthy controls, serum APRIL levels were significantly higher in IgAN patients (p = 0.0001) and associated with severity of disease. 28636766 2017
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis
0.030 AlteredExpression disease BEFREE Taken together, our data indicate that antibody disorders in IgAN associate with TLR9-induced aberrant expression of APRIL in tonsillar GC B cells. 27920152 2017
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis
0.030 Biomarker disease BEFREE These data indicated that TW may be involved in IgA production in the tonsils of IgAN patients, inhibiting IgA class switching in IgAN patients through the cooperative roles of AID, TGF-β1, BAFF, and APRIL, highlighting a promising strategy for therapeutic intervention in IgAN. 29312588 2017