Disease: Autoimmune Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.060 Biomarker group BEFREE The B-cell survival factors APRIL and BLyS are important for B-cell maturation and activation and contribute to human autoimmune diseases. 20890272 2011
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.060 PosttranslationalModification group BEFREE APRIL and BAFF are involved in a variety of tumor and autoimmune diseases, including B-cell malignancies. 15070697 2004
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.060 Biomarker group BEFREE Therefore, Anp32b appears to fulfill a role in regulating adequate adaptive immune responses and, hence, may be involved in dysregulation of pathways leading to autoimmune disorders and/or immune deficiencies. 30890743 2019
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.060 Biomarker group BEFREE These findings raise the possibility that active BLyS/APRIL heterotrimers may play a role in rheumatic and other autoimmune diseases and that other members of the TNF ligand superfamily may also form active soluble heterotrimers. 12370363 2002
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.060 Biomarker group BEFREE BAFF can also, in autoimmune disease form heterotrimers with APRIL but the control and function of these heterotrimers remain unclear. 18295728 2008
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.060 Biomarker group BEFREE APRIL may serve as a down modulator of serological and/or clinical autoimmunity in patients with SLE. 15308519 2004