Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009447
Disease: Common Variable Immunodeficiency
Common Variable Immunodeficiency
0.040 Biomarker disease BEFREE Whilst statistical analysis of ELISA results showed significant differences between patients and healthy controls, in our set of patients functional tests yielded no evidence for an involvement of autoantibodies against BAFF, APRIL, or IL-21 in the pathogenesis of CVID or sIgAD. 28651547 2017
CUI: C0009447
Disease: Common Variable Immunodeficiency
Common Variable Immunodeficiency
0.040 AlteredExpression disease BEFREE Mature B-cell defects lead to Common Variable Immunodeficiency (CVID), which is associated with elevated serum levels of BAFF and APRIL. 24809296 2014
CUI: C0009447
Disease: Common Variable Immunodeficiency
Common Variable Immunodeficiency
0.040 Biomarker disease BEFREE This review delineates the contribution of interleukin (IL)-1, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12, IL-21, interferons, tumor necrosis factor (TNF)-α, IL-17, APRIL (a proliferation inducing ligand) and BAFF (B cell activating factor) in CVID disease and outline their potential therapeutic implications in these patients. 24827633 2014
CUI: C0009447
Disease: Common Variable Immunodeficiency
Common Variable Immunodeficiency
0.040 AlteredExpression disease BEFREE High serum levels of BAFF, APRIL, and TACI in common variable immunodeficiency. 17556024 2007