Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2062441
Disease: Influenza A
Influenza A
0.020 Biomarker disease BEFREE Using a CRISPR approach, we show that the human <u>a</u>cidic <u>n</u>uclear <u>p</u>hosphoproteins (ANPs) ANP32A and ANP32B are functionally redundant but essential host factors for mammalian-adapted influenza A virus (IAV) and influenza B virus (IBV) replication in human cells. 31217244 2019
CUI: C2062441
Disease: Influenza A
Influenza A
0.020 Biomarker disease BEFREE Our findings strongly support ANP32A and ANP32B as key factors for both virus replication and adaptation.<b>IMPORTANCE</b> The key host factors involved in the influenza A viral polymerase activity and RNA replication remain largely unknown. 30996088 2019